Inulin Labeled With Chromium 51 for Determination of Glomerular Filtration Rate

Barry J. Materson, Albert E. Johnson, Eliseo C. Perez Stable

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Glomerular filtration rate (GFR) was determined in 12 patients by simultaneous clearance of inulin and inulin labeled with chromium 51 (inulin51Cr). Paired GFRs calculated by the classic C=UV/P formula showed excellent correlation (r±0.995; P<0.001; y =1.01x - 2.03, where y indicates clearance of inulin5Cr, and x indicates clearance of inulin). The clearance ratio was 0.975. Determination of GFR with inulin51Cr proved to be faster, cheaper, and more practical than with inulin. This compound makes GFR determinations readily available for clinical use.

Original languageEnglish (US)
Pages (from-to)94-96
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Volume207
Issue number1
DOIs
StatePublished - Jan 6 1969

ASJC Scopus subject areas

  • Medicine(all)

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