Introduction to techniques in developmental electrobiology

Birgit Rose, John Barrett

Research output: Contribution to journalArticlepeer-review


This chapter introduces electrobiological techniques and outlines the general principles involved. It points out limitations and possible pitfalls. The sensitive monitoring power of electrobiological techniques promises continuing new insights into the development of organisms in general and of the nervous system in particular. Because the nervous system utilizes electrical changes as the basis for its major functional activity, electrical recording methods are uniquely advantageous in monitoring its functional development. In addition, intracellular electrical recordings, particularly the more refined approaches such as voltage clamping and membrane noise analysis, provides a means for investigating the basic ionic mechanisms underlying neuron or cell membrane function as well as for studying the development of the various membrane properties during differentiation. Examples from developmental biology are used in the chapter to illustrate the application of some of the methods.

Original languageEnglish (US)
Pages (from-to)1-30
Number of pages30
JournalCurrent Topics in Developmental Biology
Issue numberC
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology


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