Intravitreal bevacizumab (Avastin) injection as primary treatment of inflammatory choroidal neovascularization

Alfredo Adán, Carlos Mateo, Rafael Navarro, Elena Bitrian, Ricardo P. Casaroli-Marano

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

OBJECTIVE: To assess the effects of intravitreal bevacizumab injection as primary treatment of inflammatory choroidal neovascularization (CNV). METHODS: Data for nine consecutive patients with newly diagnosed inflammatory CNV who were treated with intravitreal bevacizumab (1.25 mg) injection were reviewed retrospectively. Main outcome measures were best-corrected visual acuity, foveal thickness measured by optical coherence tomography (OCT), and complete resolution of CNV. RESULTS: CNV resolved completely in 9 (100%) of 9 affected eyes. At the last examination, visual acuity was improved in 8 eyes (88.8%), stable in 1 (11.2%), and worse in 0. Over a mean follow-up of 7.1 months (range, 6-10 months), 7 eyes received 1 injection, 1 eye developed CNV recurrence and required a second injection, and 1 eye required a third injection. Foveal thickness by OCT decreased significantly (P = 0.049) after treatment. CONCLUSION: In this small case series of eyes with limited follow-up, intravitreal bevacizumab injection for treatment of inflammatory CNV was found to be safe and was associated with favorable visual outcomes for both subfoveal and juxtafoveal or extrafoveal inflammatory CNV.

Original languageEnglish (US)
Pages (from-to)1180-1186
Number of pages7
JournalRetina
Volume27
Issue number9
DOIs
StatePublished - Nov 2007
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint

Dive into the research topics of 'Intravitreal bevacizumab (Avastin) injection as primary treatment of inflammatory choroidal neovascularization'. Together they form a unique fingerprint.

Cite this