Intravenous leiomyomatosis with intracardiac extension: a single-institution experience

Micheal J. Worley, Anate Aelion, Thomas A. Caputo, Kenneth C. Kent, Arash Salemi, Karl H. Krieger, Michael J. Goldstein, Dennis Y. Kuo, Brian M. Slomovitz

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Objective: The aim of this study was to outline the surgical management and outcomes for patients diagnosed with intravenous leiomyomatosis with intracardiac extension at a single institution. Study Design: This was a retrospective review of patients diagnosed with intravenous leiomyomatosis with intracardiac extension between 2002-2008. Results: Four patients were identified. The surgical approach in 3 (75%) patients was a single-stage operation. Four (100%) patients presented with cardiac symptoms: 3 (75%) with syncope and 1 (25%) with an abnormal electrocardiogram. Mean age at presentation was 48 years (range, 42-58 years). Complete resection of tumor was obtained in 1 (25%) patient and 3 (75%) patients experienced incomplete resection. Mean follow-up, including surveillance imaging, was 25.5 months (range, 8-57 months) and all 4 patients (100%) are currently free of recurrence. Conclusion: Surgical excision remains an effective therapy for treating patients with benign metastasizing leiomyomatosis. Incomplete surgical resection may result in favorable response.

Original languageEnglish (US)
Pages (from-to)574.e1-574.e5
JournalAmerican journal of obstetrics and gynecology
Volume201
Issue number6
DOIs
StatePublished - Dec 2009

Keywords

  • cardiac mass
  • fibroid
  • intravenous leiomyomatosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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    Worley, M. J., Aelion, A., Caputo, T. A., Kent, K. C., Salemi, A., Krieger, K. H., Goldstein, M. J., Kuo, D. Y., & Slomovitz, B. M. (2009). Intravenous leiomyomatosis with intracardiac extension: a single-institution experience. American journal of obstetrics and gynecology, 201(6), 574.e1-574.e5. https://doi.org/10.1016/j.ajog.2009.06.037