Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE2 for cervical dilation prior to suction curettage

Arthur G. Shapiro, Kenneth Lasseter, Ana Cobiella, Mario Domenzain

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The use of prostaglandin for "priming" the cervix may avoid the pain and potential injuries associated with the rapid instrument dilation of a suction curettage. Prostaglandins appear to be able to soften and dilate the cervix, so that mechanical dilation is usually unnecessary. The results of the present study indicate that a single 16,16-dimethyl PGE2 vaginal suppository is apparently adequate for achieving this effect as well as having relatively minimal side effects.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalInternational Journal of Gynecology and Obstetrics
Issue number2
StatePublished - Apr 1982


  • 16,16-Dimethyl prostaglandin E
  • Cervical dilation
  • Cervical effacement
  • Cervical priming
  • Prostaglandin
  • Suction curettage

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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