Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE2 for cervical dilation prior to suction curettage

Arthur G. Shapiro; Kenneth Lasseter; Ana Cobiella; Mario Domenzain

doi:10.1016/0020-7292(82)90026-1

Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE₂ for cervical dilation prior to suction curettage

Arthur G. Shapiro, Kenneth Lasseter, Ana Cobiella, Mario Domenzain

Obstetrics & Gynecology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The use of prostaglandin for "priming" the cervix may avoid the pain and potential injuries associated with the rapid instrument dilation of a suction curettage. Prostaglandins appear to be able to soften and dilate the cervix, so that mechanical dilation is usually unnecessary. The results of the present study indicate that a single 16,16-dimethyl PGE₂ vaginal suppository is apparently adequate for achieving this effect as well as having relatively minimal side effects.

Original language	English (US)
Pages (from-to)	137-140
Number of pages	4
Journal	International Journal of Gynecology and Obstetrics
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/0020-7292(82)90026-1
State	Published - Apr 1982

Keywords

16,16-Dimethyl prostaglandin E
Cervical dilation
Cervical effacement
Cervical priming
Prostaglandin
Suction curettage

ASJC Scopus subject areas

Obstetrics and Gynecology

Access to Document

10.1016/0020-7292(82)90026-1

Cite this

@article{adf383104d4046c28a9b4f648ba6994c,

title = "Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE2 for cervical dilation prior to suction curettage",

abstract = "The use of prostaglandin for {"}priming{"} the cervix may avoid the pain and potential injuries associated with the rapid instrument dilation of a suction curettage. Prostaglandins appear to be able to soften and dilate the cervix, so that mechanical dilation is usually unnecessary. The results of the present study indicate that a single 16,16-dimethyl PGE2 vaginal suppository is apparently adequate for achieving this effect as well as having relatively minimal side effects.",

keywords = "16,16-Dimethyl prostaglandin E, Cervical dilation, Cervical effacement, Cervical priming, Prostaglandin, Suction curettage",

author = "Shapiro, {Arthur G.} and Kenneth Lasseter and Ana Cobiella and Mario Domenzain",

note = "Funding Information: {\textquoteleft}This research was made possible by a grant from Upjohn Company and with the collaboration of Dr. Edward Southern and Glenn Gutnecht of the Upjohn Company. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1982",

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T1 - Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE2 for cervical dilation prior to suction curettage

AU - Shapiro, Arthur G.

AU - Lasseter, Kenneth

AU - Cobiella, Ana

AU - Domenzain, Mario

N1 - Funding Information: ‘This research was made possible by a grant from Upjohn Company and with the collaboration of Dr. Edward Southern and Glenn Gutnecht of the Upjohn Company. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1982/4

Y1 - 1982/4

N2 - The use of prostaglandin for "priming" the cervix may avoid the pain and potential injuries associated with the rapid instrument dilation of a suction curettage. Prostaglandins appear to be able to soften and dilate the cervix, so that mechanical dilation is usually unnecessary. The results of the present study indicate that a single 16,16-dimethyl PGE2 vaginal suppository is apparently adequate for achieving this effect as well as having relatively minimal side effects.

AB - The use of prostaglandin for "priming" the cervix may avoid the pain and potential injuries associated with the rapid instrument dilation of a suction curettage. Prostaglandins appear to be able to soften and dilate the cervix, so that mechanical dilation is usually unnecessary. The results of the present study indicate that a single 16,16-dimethyl PGE2 vaginal suppository is apparently adequate for achieving this effect as well as having relatively minimal side effects.

KW - 16,16-Dimethyl prostaglandin E

KW - Cervical dilation

KW - Cervical effacement

KW - Cervical priming

KW - Prostaglandin

KW - Suction curettage

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