Intraosseous venous malformations of the zygoma: Clarification of misconceptions regarding diagnosis and management

Michael V. DeFazio, Wrood Kassira, Liliana Camison, Lauren Meshkov, Philip G. Robinson, Henry K. Kawamoto, Seth R. Thaller

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Primary intraosseous venous malformations affecting the zygoma are rare vascular lesions, with only 35 cases reported in the surgical literature. Despite the establishment of the binary classification system, which serves to distinguish vascular tumors from malformations, inappropriate use of the term ''hemangioma'' to describe a variety of distinct vascular anomalies remains widespread. The authors present 3 cases of zygomatic intraosseous venous malformations and summarize the clinical, radiographic, and immunohistochemical features of these lesions. In each case, an insidious clinical course, combined with the pathognomonic finding of radiating trabeculae on computed tomography, suggests the diagnosis of intraosseous venous malformation. Negative glucose transporter isoform 1 immunoreactivity and histopathological analysis were used to reinforce this diagnosis in 1 patient. Management was individualized in each case, based on symptom complex and aesthetic concern. Given that the therapeutic approach to vascular anomalies is dependent on accurate diagnosis, resolution of semantic matters will optimize the management of these lesions.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalAnnals of plastic surgery
Issue number3
StatePublished - Jan 1 2014


  • Facial bone
  • Intraosseous hemangioma
  • Intraosseous venous malformation
  • Vascular malformation
  • Zygoma

ASJC Scopus subject areas

  • Surgery


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