Intraocular tuberculosis

Nicholas J. Cutrufello, Petros C. Karakousis, Jane Fishler, Thomas A. Albini

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

Intraocular manifestations of tuberculosis (TB) are rare, but TB infection is common worldwide, especially in developing economies, and in immigrant populations and immunocompromised patients in developed nations. The current review focuses on the clinical characteristics and diagnostic modalities useful in the diagnosis of intraocular TB. Specifically, IFN-γ Release Assays (IGRAs), antigen-detection assays, and polymerase chain reactions will be discussed. Clinical management of TB patients includes counseling and testing for HIV infection. The use of corticosteroids along with anti-tuberculous medications and special therapeutic considerations in immunocompromised patients are discussed.

Original languageEnglish (US)
Pages (from-to)281-291
Number of pages11
JournalOcular Immunology and Inflammation
Volume18
Issue number4
DOIs
StatePublished - Aug 1 2010

Keywords

  • HIV
  • IFN-γ release assays (IGRA)
  • Lipoarabinomannan (LAM)
  • Ocular tuberculosis' PCR

ASJC Scopus subject areas

  • Ophthalmology
  • Immunology and Allergy

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