TY - JOUR
T1 - Intraocular pressure and calculated diastolic ocular perfusion pressure during three simulated steps of phacoemulsification in vivo
AU - Zhao, Yune
AU - Li, Xingyu
AU - Tao, Aizhu
AU - Wang, Jianhua
AU - Lu, Fan
PY - 2009
Y1 - 2009
N2 - Purpose: To investigate the fluctuations of directly measured intraocular pressure (IOP) and induced diastolic ocular perfusion pressure (DOPP) during three simulated steps of phacoemulsification in vivo. Methods: Twenty-five eyes of 25 patients who underwent phacoemulsification were evaluated. A pressure transducer was inserted into the anterior chamber to measure IOP directly. The cortical cleanup and viscoelastic removal, nuclear disassembly, and anterior capsular polishing stages of phacoemulsification were simulated. Baseline, static, and dynamic IOP measurements at each stage were conducted before a routine phacoemulsification procedure was performed. DOPP was determined as the difference between diastolic blood pressure and IOP. Results: The directly measured IOP fluctuated from 13 ± 4.7 to 96 ± 6.2 mm Hg during the simulated steps of phacoemulsification (repeated-measurement ANOVA, P < 0.001). It was elevated more than 39 mm Hg compared with the baseline in static and dynamic measurements (post hoc, P < 0.001). Static DOPPs were lower than 0 mm Hg in all cases during simulated cortical cleanup and viscoelastic removal and in 19 cases during simulated nuclear disassembly. Dynamic DOPPs were lower than 0 mm Hg in 14 cases during simulated cortical cleanup and viscoelastic removal. Conclusions: IOP and DOPP fluctuate widely during simulated steps of phacoemulsification. Further studies may be needed to establish the effect of the transient fluctuations in DOPP on visual function.
AB - Purpose: To investigate the fluctuations of directly measured intraocular pressure (IOP) and induced diastolic ocular perfusion pressure (DOPP) during three simulated steps of phacoemulsification in vivo. Methods: Twenty-five eyes of 25 patients who underwent phacoemulsification were evaluated. A pressure transducer was inserted into the anterior chamber to measure IOP directly. The cortical cleanup and viscoelastic removal, nuclear disassembly, and anterior capsular polishing stages of phacoemulsification were simulated. Baseline, static, and dynamic IOP measurements at each stage were conducted before a routine phacoemulsification procedure was performed. DOPP was determined as the difference between diastolic blood pressure and IOP. Results: The directly measured IOP fluctuated from 13 ± 4.7 to 96 ± 6.2 mm Hg during the simulated steps of phacoemulsification (repeated-measurement ANOVA, P < 0.001). It was elevated more than 39 mm Hg compared with the baseline in static and dynamic measurements (post hoc, P < 0.001). Static DOPPs were lower than 0 mm Hg in all cases during simulated cortical cleanup and viscoelastic removal and in 19 cases during simulated nuclear disassembly. Dynamic DOPPs were lower than 0 mm Hg in 14 cases during simulated cortical cleanup and viscoelastic removal. Conclusions: IOP and DOPP fluctuate widely during simulated steps of phacoemulsification. Further studies may be needed to establish the effect of the transient fluctuations in DOPP on visual function.
UR - http://www.scopus.com/inward/record.url?scp=66849091260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=66849091260&partnerID=8YFLogxK
U2 - 10.1167/iovs.08-2996
DO - 10.1167/iovs.08-2996
M3 - Article
C2 - 19168897
AN - SCOPUS:66849091260
VL - 50
SP - 2927
EP - 2931
JO - Investigative Ophthalmology and Visual Science
JF - Investigative Ophthalmology and Visual Science
SN - 0146-0404
IS - 6
ER -