Intramedullary spinal cord metastases, mainly of nonneurogenic origin

M. Judith Post, Robert Quencer, Barth A Green, B. M. Montalvo, J. A. Tobias, J. J. Sowers, I. H. Levin

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The clinical data and imaging studies of 12 patients with intramedullary metastases were reviewed retrospectively to see if these lesions had a typical radiographic appearance and to determine the sensitivity of the various radiologic examinations. The lesions were identified antemortem by either myelography, CT, MR, and/or intraoperative spinal sonography (IOSS). Final diagnosis was based on biopsy material from either the spinal cord lesion, another metastatic site, and/or the primary tumor. Ten patients had primary tumors located outside the central nervous system, while only two patients had primary brain tumors. Metrizamide myelography and CT demonstrated a definite intramedullary mass in nine of 11 patients. In five patients the mass was relatively small, well-defined, single, and resembled a primary spinal cord neoplasm. In the other four patients, longer and sometimes several segments of the cord were involved. These appeared irregular and nodular and were often associated with intradural lesions at separate sites. MR detected not only enlargement and abnormal signal in the cord but also clinically unsuspected brains lesions. IOSS localized lesions for biopsy and monitored tumor resection. These various imaging procedures showed that cord metastases were often more extensive than anticipated clinically. Spread of tumor into the spinal and intracranial subarachnoid space was common. Imaging of the entire spinal canal and brain, preferably with MR, is therefore recommended to aid in diagnosis, prognosis, and treatment.

Original languageEnglish
Pages (from-to)1015-1022
Number of pages8
JournalAmerican Journal of Roentgenology
Volume148
Issue number5
StatePublished - Jul 6 1987

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Spinal Cord
Neoplasm Metastasis
Myelography
Ultrasonography
Neoplasms
Spinal Cord Neoplasms
Metrizamide
Biopsy
Subarachnoid Space
Spinal Canal
Brain
Brain Neoplasms
Central Nervous System
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Judith Post, M., Quencer, R., Green, B. A., Montalvo, B. M., Tobias, J. A., Sowers, J. J., & Levin, I. H. (1987). Intramedullary spinal cord metastases, mainly of nonneurogenic origin. American Journal of Roentgenology, 148(5), 1015-1022.

Intramedullary spinal cord metastases, mainly of nonneurogenic origin. / Judith Post, M.; Quencer, Robert; Green, Barth A; Montalvo, B. M.; Tobias, J. A.; Sowers, J. J.; Levin, I. H.

In: American Journal of Roentgenology, Vol. 148, No. 5, 06.07.1987, p. 1015-1022.

Research output: Contribution to journalArticle

Judith Post, M, Quencer, R, Green, BA, Montalvo, BM, Tobias, JA, Sowers, JJ & Levin, IH 1987, 'Intramedullary spinal cord metastases, mainly of nonneurogenic origin', American Journal of Roentgenology, vol. 148, no. 5, pp. 1015-1022.
Judith Post M, Quencer R, Green BA, Montalvo BM, Tobias JA, Sowers JJ et al. Intramedullary spinal cord metastases, mainly of nonneurogenic origin. American Journal of Roentgenology. 1987 Jul 6;148(5):1015-1022.
Judith Post, M. ; Quencer, Robert ; Green, Barth A ; Montalvo, B. M. ; Tobias, J. A. ; Sowers, J. J. ; Levin, I. H. / Intramedullary spinal cord metastases, mainly of nonneurogenic origin. In: American Journal of Roentgenology. 1987 ; Vol. 148, No. 5. pp. 1015-1022.
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