Intralesional treatment for keloids and hypertrophic scars

A review

Jennifer A. Ledon, Jessica Savas, Katlein Franca, Anna Chacon, Keyvan Nouri

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Background Although differing in clinical presentation and prognosis, keloids and hypertrophic scars are generally characterized by abnormally proliferative scar tissue and are extremely debilitating. Several intralesional therapies have been studied in attempts to find a universally safe and effective modality, of which there are currently none. Objective To provide a comprehensive review of current intralesional treatment modalities for keloids and hypertrophic scars. Methods and Materials A PubMed search was performed for literature pertaining to intralesional treatment modalities for keloids and hypertrophic scars. References from retrieved articles were also considered for review. Results and Conclusion Many intralesional therapies for keloids and hypertrophic scars are currently available to physicians and patients. Mechanisms of action and side effect profiles vary between these agents, and new approaches to keloids and hypertrophic scars are frequently being explored. Randomized controlled trials are needed to assess these new and promising modalities fully.

Original languageEnglish
Pages (from-to)1745-1757
Number of pages13
JournalDermatologic Surgery
Volume39
Issue number12
DOIs
StatePublished - Dec 1 2013

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Hypertrophic Cicatrix
Keloid
Therapeutics
PubMed
Cicatrix
Randomized Controlled Trials
Physicians

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

Intralesional treatment for keloids and hypertrophic scars : A review. / Ledon, Jennifer A.; Savas, Jessica; Franca, Katlein; Chacon, Anna; Nouri, Keyvan.

In: Dermatologic Surgery, Vol. 39, No. 12, 01.12.2013, p. 1745-1757.

Research output: Contribution to journalArticle

Ledon, Jennifer A. ; Savas, Jessica ; Franca, Katlein ; Chacon, Anna ; Nouri, Keyvan. / Intralesional treatment for keloids and hypertrophic scars : A review. In: Dermatologic Surgery. 2013 ; Vol. 39, No. 12. pp. 1745-1757.
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