Intracardiac infusion of acetylcholine in primary pulmonary hypertension

Philip Samet; William H. Bernstein; Jack Widrich

doi:10.1016/0002-8703(60)90202-7

Intracardiac infusion of acetylcholine in primary pulmonary hypertension

Philip Samet, William H. Bernstein, Jack Widrich

Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Two cases of primary pulmonary hypertension are presented, and the results of right heart catheterization are given. Infusion of acetylcholine caused large decreases in pulmonary arterial pressure in one subject, both at rest and during exercise. In the second subject, infusion of acetylcholine resulted in a lesser but still significant decrease in pulmonary arterial pressure. The criteria that must be met before conclusions are drawn as to the existence of vasodilation or vasoconstriction in the pulmonary vascular bed are discussed.

Original language	English (US)
Pages (from-to)	433-439
Number of pages	7
Journal	American Heart Journal
Volume	60
Issue number	3
DOIs	https://doi.org/10.1016/0002-8703(60)90202-7
State	Published - Sep 1960

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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abstract = "Two cases of primary pulmonary hypertension are presented, and the results of right heart catheterization are given. Infusion of acetylcholine caused large decreases in pulmonary arterial pressure in one subject, both at rest and during exercise. In the second subject, infusion of acetylcholine resulted in a lesser but still significant decrease in pulmonary arterial pressure. The criteria that must be met before conclusions are drawn as to the existence of vasodilation or vasoconstriction in the pulmonary vascular bed are discussed.",

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