TY - JOUR
T1 - Intracardiac infusion of acetylcholine in primary pulmonary hypertension
AU - Samet, Philip
AU - Bernstein, William H.
AU - Widrich, Jack
PY - 1960/9
Y1 - 1960/9
N2 - Two cases of primary pulmonary hypertension are presented, and the results of right heart catheterization are given. Infusion of acetylcholine caused large decreases in pulmonary arterial pressure in one subject, both at rest and during exercise. In the second subject, infusion of acetylcholine resulted in a lesser but still significant decrease in pulmonary arterial pressure. The criteria that must be met before conclusions are drawn as to the existence of vasodilation or vasoconstriction in the pulmonary vascular bed are discussed.
AB - Two cases of primary pulmonary hypertension are presented, and the results of right heart catheterization are given. Infusion of acetylcholine caused large decreases in pulmonary arterial pressure in one subject, both at rest and during exercise. In the second subject, infusion of acetylcholine resulted in a lesser but still significant decrease in pulmonary arterial pressure. The criteria that must be met before conclusions are drawn as to the existence of vasodilation or vasoconstriction in the pulmonary vascular bed are discussed.
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U2 - 10.1016/0002-8703(60)90202-7
DO - 10.1016/0002-8703(60)90202-7
M3 - Article
C2 - 14441214
AN - SCOPUS:0004239928
VL - 60
SP - 433
EP - 439
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 3
ER -