Intraarterial Platelet Infusion for Patients with Intractable Gastrointestinal Hemorrhage and Severe Refractory Thrombocytopenia

David C. Madoff, Michael J. Wallace, Benjamin Lichtiger, Krishna V Komanduri, William A. Ross, Aida B. Narvios, C. Lee Parmley

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Transarterial therapies used for the treatment of acute nonvariceal gastrointestinal (GI) hemorrhage have traditionally included vasopressin infusion and embolization. However, for patients with diffuse or multifocal hemorrhage and severe refractory thrombocytopenia, these options are suboptimal because platelet counts and coagulation parameters may not be adequate to allow for the formation of a stable clot. Herein two such patients treated with direct intraarterial (IA) infusion of platelets into the vascular territory supplying the hemorrhage are described. In both patients, after IA platelet infusion, blood product requirements were immediately reduced, bleeding from the GI tract resolved by clinical and laboratory criteria, and no significant bowel ischemia was seen.

Original languageEnglish
Pages (from-to)393-397
Number of pages5
JournalJournal of Vascular and Interventional Radiology
Volume15
Issue number4
StatePublished - Apr 1 2004
Externally publishedYes

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Intra Arterial Infusions
Gastrointestinal Hemorrhage
Thrombocytopenia
Blood Platelets
Hemorrhage
Vasopressins
Platelet Count
Blood Vessels
Gastrointestinal Tract
Ischemia
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Intraarterial Platelet Infusion for Patients with Intractable Gastrointestinal Hemorrhage and Severe Refractory Thrombocytopenia. / Madoff, David C.; Wallace, Michael J.; Lichtiger, Benjamin; Komanduri, Krishna V; Ross, William A.; Narvios, Aida B.; Parmley, C. Lee.

In: Journal of Vascular and Interventional Radiology, Vol. 15, No. 4, 01.04.2004, p. 393-397.

Research output: Contribution to journalArticle

Madoff, David C. ; Wallace, Michael J. ; Lichtiger, Benjamin ; Komanduri, Krishna V ; Ross, William A. ; Narvios, Aida B. ; Parmley, C. Lee. / Intraarterial Platelet Infusion for Patients with Intractable Gastrointestinal Hemorrhage and Severe Refractory Thrombocytopenia. In: Journal of Vascular and Interventional Radiology. 2004 ; Vol. 15, No. 4. pp. 393-397.
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