Intestinal and multivisceral transplantation at the University of Miami.

Gennaro Selvaggi, Seigo Nishida, David Levi, Jang Moon, Eddie Island, Akin Tekin, Debbie Weppler, Andreas Tzakis

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

At the University of Miami Liver and GI Transplant Program, over 300 intestinal transplant procedures were performed in the last 15 years in adult and pediatric recipients. Good patient and graft survival rates are now achievable. Rejection remains the complication that is most difficult to prevent and manage. Induction with antilymphocyte agents, followed by maintenance with tacrolimus, is the preferred immunosuppression protocol at our center. We have expanded the use of multivisceral transplantation in pediatric recipients with short gut and significant liver dysfunction from parenteral nutrition. We also advocate the use of large intestine as part of the intestinal graft as well as inclusion of the spleen in multivisceral grafts, which in our experience can be safely accomplished. The future of intestinal transplantation lies in the use of noninvasive markers of intestinal rejection, and continued refinements in immunosuppression protocols.

Original languageEnglish (US)
Pages (from-to)211-217
Number of pages7
JournalClinical transplants
StatePublished - 2009

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Selvaggi, G., Nishida, S., Levi, D., Moon, J., Island, E., Tekin, A., Weppler, D., & Tzakis, A. (2009). Intestinal and multivisceral transplantation at the University of Miami. Clinical transplants, 211-217.