Abstract
The effects of cardiopulmonary bypass using hemodilution on interstitial fluid pressure were measured using the Scholander wick technique. In 10 mongrel dogs, interstitial fluid pressure was measured in subcutaneous tissue, skeletal muscle, stomach, and left ventricle before and during 2 hours of cardiopulmonary bypass. Changes in interstitial fluid pressure were correlated with plasma colloidal osmotic pressure and duration of bypass. In subcutaneous tissue and skeletal muscle, interstitial fluid pressure increased during bypass; it did not change in the stomach. End-diastolic interstitial fluid pressure in the left ventricle increased significantly. These increases in pressure were presumably due to an increase in interstitial water. The rise in interstitial fluid pressure acts to partially neutralize the fall in plasma colloidal osmotic pressure.
| Original language | English |
|---|---|
| Pages (from-to) | 536-542 |
| Number of pages | 7 |
| Journal | Annals of Thoracic Surgery |
| Volume | 30 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 1980 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
Interstitial fluid pressure changes during cardiopulmonary bypass. / Rosenkranz, Eliot; Utley, J. R.; Menninger, F. J.; Dembitsky, W. P.; Hargens, A. R.; Peters, R. M.
In: Annals of Thoracic Surgery, Vol. 30, No. 6, 01.12.1980, p. 536-542.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interstitial fluid pressure changes during cardiopulmonary bypass
AU - Rosenkranz, Eliot
AU - Utley, J. R.
AU - Menninger, F. J.
AU - Dembitsky, W. P.
AU - Hargens, A. R.
AU - Peters, R. M.
PY - 1980/12/1
Y1 - 1980/12/1
N2 - The effects of cardiopulmonary bypass using hemodilution on interstitial fluid pressure were measured using the Scholander wick technique. In 10 mongrel dogs, interstitial fluid pressure was measured in subcutaneous tissue, skeletal muscle, stomach, and left ventricle before and during 2 hours of cardiopulmonary bypass. Changes in interstitial fluid pressure were correlated with plasma colloidal osmotic pressure and duration of bypass. In subcutaneous tissue and skeletal muscle, interstitial fluid pressure increased during bypass; it did not change in the stomach. End-diastolic interstitial fluid pressure in the left ventricle increased significantly. These increases in pressure were presumably due to an increase in interstitial water. The rise in interstitial fluid pressure acts to partially neutralize the fall in plasma colloidal osmotic pressure.
AB - The effects of cardiopulmonary bypass using hemodilution on interstitial fluid pressure were measured using the Scholander wick technique. In 10 mongrel dogs, interstitial fluid pressure was measured in subcutaneous tissue, skeletal muscle, stomach, and left ventricle before and during 2 hours of cardiopulmonary bypass. Changes in interstitial fluid pressure were correlated with plasma colloidal osmotic pressure and duration of bypass. In subcutaneous tissue and skeletal muscle, interstitial fluid pressure increased during bypass; it did not change in the stomach. End-diastolic interstitial fluid pressure in the left ventricle increased significantly. These increases in pressure were presumably due to an increase in interstitial water. The rise in interstitial fluid pressure acts to partially neutralize the fall in plasma colloidal osmotic pressure.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019120112&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(10)61727-4
DO - 10.1016/S0003-4975(10)61727-4
M3 - Article
C2 - 7469575
AN - SCOPUS:0019120112
VL - 30
SP - 536
EP - 542
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 6
ER -