@article{b5683f34869e4b7ab5c14047f4a07d59,
title = "Interpreting spatial and temporal neural activity through a recurrent neural network brain-machine interface",
abstract = "We propose the use of optimized brain-machine interface (BMI) models for interpreting the spatial and temporal neural activity generated in motor tasks. In this study, a nonlinear dynamical neural network is trained to predict the hand position of primates from neural recordings in a reaching task paradigm. We first develop a method to reveal the role attributed by the model to the sampled motor, premotor, and parietal cortices in generating hand movements. Next, using the trained model weights, we derive a temporal sensitivity measure to asses how the model utilized the sampled cortices and neurons in real-time during BMI testing.",
keywords = "Analysis of neural activity, Brain-machine interface (BMI), Motor systems, Nonlinear models, Recurrent neural network, Spatio-temporal",
author = "Sanchez, {Justin C.} and Deniz Erdogmus and Nicolelis, {Miguel A.L.} and Johan Wessberg and Principe, {Jose C.}",
note = "Funding Information: Manuscript received February 15, 2005; accepted February 20, 2005. This work was supported by the Defense Advanced Research Projects Agengy under Project N66001-02-C-8022. J. C. Sanchez is with the Department of Pediatrics Division of Neurology, University of Florida, Gainesville, FL 32611 USA (e-mail: justin@ cnel.ufl.edu). D. Erdogmus is with the Department of Computer Science Engineering, Oregon Health and Science University, Beaverton, OR 97006 USA. M. A. L. Nicolelis is with the Department of Neurobiology, Duke University, Durham, NC 27710 USA. J. Wessberg is with the Department of Physiology, G{\"o}teborg University, 405 30 G{\"o}teborg, Sweden. J. C. Principe is with the Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611 USA. Digital Object Identifier 10.1109/TNSRE.2005.847382",
year = "2005",
month = jun,
doi = "10.1109/TNSRE.2005.847382",
language = "English (US)",
volume = "13",
pages = "213--219",
journal = "IEEE Transactions on Neural Systems and Rehabilitation Engineering",
issn = "1534-4320",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "2",
}