Interpreting and reporting molecular diagnostic tests

Ranjini Valiathan, Deshratn Asthana

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Molecular testing methods have become the infectious disease testing method of choice for many laboratories and healthcare professionals in recent years. Molecular tests provide highly sensitive and reliable results, which can detect infectious pathogens both qualitatively and quantitatively and can produce timely test results enabling better and cheaper patient care than conventional culture-based or antigen detection methods, and it is more efficient in the detection of organisms that are nonviable or uncultivable. Today, molecular methods have become an essential part of the clinical microbiology laboratory, particularly for the detection and characterization of virus infections and for the diagnosis of diseases due to fastidious bacteria. The advantages of rapid turnaround time and high sensitivity and specificity are appealing. With the introduction of automation for the various stages of DNA or RNA extraction, amplification and product detection together with real-time PCR, molecular laboratories have become more efficient and cost-effective.

Original languageEnglish
Title of host publicationMolecular Diagnostics of Infectious Diseases
PublisherWalter de Gruyter GmbH and Co. KG
Pages67-76
Number of pages10
ISBN (Print)9783110214857
DOIs
StatePublished - May 27 2010
Externally publishedYes

Fingerprint

Molecular Pathology
Routine Diagnostic Tests
Automation
Virus Diseases
Microbiology
Communicable Diseases
Real-Time Polymerase Chain Reaction
Patient Care
RNA
Bacteria
Delivery of Health Care
Antigens
Costs and Cost Analysis
Sensitivity and Specificity
DNA

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Valiathan, R., & Asthana, D. (2010). Interpreting and reporting molecular diagnostic tests. In Molecular Diagnostics of Infectious Diseases (pp. 67-76). Walter de Gruyter GmbH and Co. KG. https://doi.org/10.1515/9783110214864

Interpreting and reporting molecular diagnostic tests. / Valiathan, Ranjini; Asthana, Deshratn.

Molecular Diagnostics of Infectious Diseases. Walter de Gruyter GmbH and Co. KG, 2010. p. 67-76.

Research output: Chapter in Book/Report/Conference proceedingChapter

Valiathan, R & Asthana, D 2010, Interpreting and reporting molecular diagnostic tests. in Molecular Diagnostics of Infectious Diseases. Walter de Gruyter GmbH and Co. KG, pp. 67-76. https://doi.org/10.1515/9783110214864
Valiathan R, Asthana D. Interpreting and reporting molecular diagnostic tests. In Molecular Diagnostics of Infectious Diseases. Walter de Gruyter GmbH and Co. KG. 2010. p. 67-76 https://doi.org/10.1515/9783110214864
Valiathan, Ranjini ; Asthana, Deshratn. / Interpreting and reporting molecular diagnostic tests. Molecular Diagnostics of Infectious Diseases. Walter de Gruyter GmbH and Co. KG, 2010. pp. 67-76
@inbook{3f68798cd8e0409ea8552fb7b83fa1be,
title = "Interpreting and reporting molecular diagnostic tests",
abstract = "Molecular testing methods have become the infectious disease testing method of choice for many laboratories and healthcare professionals in recent years. Molecular tests provide highly sensitive and reliable results, which can detect infectious pathogens both qualitatively and quantitatively and can produce timely test results enabling better and cheaper patient care than conventional culture-based or antigen detection methods, and it is more efficient in the detection of organisms that are nonviable or uncultivable. Today, molecular methods have become an essential part of the clinical microbiology laboratory, particularly for the detection and characterization of virus infections and for the diagnosis of diseases due to fastidious bacteria. The advantages of rapid turnaround time and high sensitivity and specificity are appealing. With the introduction of automation for the various stages of DNA or RNA extraction, amplification and product detection together with real-time PCR, molecular laboratories have become more efficient and cost-effective.",
author = "Ranjini Valiathan and Deshratn Asthana",
year = "2010",
month = "5",
day = "27",
doi = "10.1515/9783110214864",
language = "English",
isbn = "9783110214857",
pages = "67--76",
booktitle = "Molecular Diagnostics of Infectious Diseases",
publisher = "Walter de Gruyter GmbH and Co. KG",

}

TY - CHAP

T1 - Interpreting and reporting molecular diagnostic tests

AU - Valiathan, Ranjini

AU - Asthana, Deshratn

PY - 2010/5/27

Y1 - 2010/5/27

N2 - Molecular testing methods have become the infectious disease testing method of choice for many laboratories and healthcare professionals in recent years. Molecular tests provide highly sensitive and reliable results, which can detect infectious pathogens both qualitatively and quantitatively and can produce timely test results enabling better and cheaper patient care than conventional culture-based or antigen detection methods, and it is more efficient in the detection of organisms that are nonviable or uncultivable. Today, molecular methods have become an essential part of the clinical microbiology laboratory, particularly for the detection and characterization of virus infections and for the diagnosis of diseases due to fastidious bacteria. The advantages of rapid turnaround time and high sensitivity and specificity are appealing. With the introduction of automation for the various stages of DNA or RNA extraction, amplification and product detection together with real-time PCR, molecular laboratories have become more efficient and cost-effective.

AB - Molecular testing methods have become the infectious disease testing method of choice for many laboratories and healthcare professionals in recent years. Molecular tests provide highly sensitive and reliable results, which can detect infectious pathogens both qualitatively and quantitatively and can produce timely test results enabling better and cheaper patient care than conventional culture-based or antigen detection methods, and it is more efficient in the detection of organisms that are nonviable or uncultivable. Today, molecular methods have become an essential part of the clinical microbiology laboratory, particularly for the detection and characterization of virus infections and for the diagnosis of diseases due to fastidious bacteria. The advantages of rapid turnaround time and high sensitivity and specificity are appealing. With the introduction of automation for the various stages of DNA or RNA extraction, amplification and product detection together with real-time PCR, molecular laboratories have become more efficient and cost-effective.

UR - http://www.scopus.com/inward/record.url?scp=84880189533&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880189533&partnerID=8YFLogxK

U2 - 10.1515/9783110214864

DO - 10.1515/9783110214864

M3 - Chapter

SN - 9783110214857

SP - 67

EP - 76

BT - Molecular Diagnostics of Infectious Diseases

PB - Walter de Gruyter GmbH and Co. KG

ER -