Interpreting and reporting molecular diagnostic tests

Ranjini Valiathan, Deshratn Asthana

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Molecular testing methods have become the infectious disease testing method of choice for many laboratories and healthcare professionals in recent years. Molecular tests provide highly sensitive and reliable results, which can detect infectious pathogens both qualitatively and quantitatively and can produce timely test results enabling better and cheaper patient care than conventional culture-based or antigen detection methods, and it is more efficient in the detection of organisms that are nonviable or uncultivable. Today, molecular methods have become an essential part of the clinical microbiology laboratory, particularly for the detection and characterization of virus infections and for the diagnosis of diseases due to fastidious bacteria. The advantages of rapid turnaround time and high sensitivity and specificity are appealing. With the introduction of automation for the various stages of DNA or RNA extraction, amplification and product detection together with real-time PCR, molecular laboratories have become more efficient and cost-effective.

Original languageEnglish (US)
Title of host publicationMolecular Diagnostics of Infectious Diseases
PublisherWalter de Gruyter GmbH and Co. KG
Pages67-76
Number of pages10
ISBN (Print)9783110214857
DOIs
StatePublished - May 27 2010

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Valiathan, R., & Asthana, D. (2010). Interpreting and reporting molecular diagnostic tests. In Molecular Diagnostics of Infectious Diseases (pp. 67-76). Walter de Gruyter GmbH and Co. KG. https://doi.org/10.1515/9783110214864