Internal sclerectomy with an automated trephine for advanced glaucoma

R. H. Brown, M. G. Lynch, D. B. Denham, Jean-Marie A Parel, Paul Palmberg, D. D. Brown

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

An automated trephine (trabecuphine) was used to perform an internal sclerectomy in seven glaucoma patients who were aphakic or had undergone previous filtering surgery that had failed or both. A patent fistula was achieved intraoperatively in all seven eyes. Postoperatively, six patients received subconjunctival injection of 5-fluorouracil (5-FU) once daily for an average of 8 days. Five of seven patients have retained a functional bleb and a controlled intraocular pressure (IOP) after sugery (follow-up, 4-24 months). The only intraoperative complication was hemorrhage from the sclerectomy site in a patient with anirida that resulted in a 20% hyphema. The hyphema cleared quickly, and the bleb has remained functional with a pressure of 12 mmHg for 9 months. The trabecuphine makes it possible to perform a glaucoma filtering operation safely from within the anterior chamber. This technique minimizes conjunctival trauma in the filtration area. The absence of a conjuctiva incision overlying the fistula simplifies the adjunctive use of antimetabolites such as 5-FU.

Original languageEnglish
Pages (from-to)728-734
Number of pages7
JournalOphthalmology
Volume95
Issue number6
StatePublished - Jan 1 1988

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Glaucoma
Hyphema
Blister
Fluorouracil
Fistula
Filtering Surgery
Antimetabolites
Intraoperative Complications
Anterior Chamber
Intraocular Pressure
Hemorrhage
Pressure
Injections
Wounds and Injuries

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Brown, R. H., Lynch, M. G., Denham, D. B., Parel, J-M. A., Palmberg, P., & Brown, D. D. (1988). Internal sclerectomy with an automated trephine for advanced glaucoma. Ophthalmology, 95(6), 728-734.

Internal sclerectomy with an automated trephine for advanced glaucoma. / Brown, R. H.; Lynch, M. G.; Denham, D. B.; Parel, Jean-Marie A; Palmberg, Paul; Brown, D. D.

In: Ophthalmology, Vol. 95, No. 6, 01.01.1988, p. 728-734.

Research output: Contribution to journalArticle

Brown, RH, Lynch, MG, Denham, DB, Parel, J-MA, Palmberg, P & Brown, DD 1988, 'Internal sclerectomy with an automated trephine for advanced glaucoma', Ophthalmology, vol. 95, no. 6, pp. 728-734.
Brown, R. H. ; Lynch, M. G. ; Denham, D. B. ; Parel, Jean-Marie A ; Palmberg, Paul ; Brown, D. D. / Internal sclerectomy with an automated trephine for advanced glaucoma. In: Ophthalmology. 1988 ; Vol. 95, No. 6. pp. 728-734.
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