Internal limiting membrane peeling: Should we do it?

W. E. Smiddy, W. Feuer

Research output: Contribution to journalArticlepeer-review


The substantial increase in macular hole surgery success rates has been attributed to various factors. Recently, the hypothesis that internal limiting membrane (ILM) peeling improves anatomic and visual success rates has been advanced. While numerous case reports have appeared addressing this issue, none have offered suitable controls to answer the question definitively. This review provides the evidence for and against ILM peeling and presents some data from one of these reports. Based on this evidence, peeling of the ILM, while not essential for anatomic or visual success, may represent a means of inducing a somewhat reproduceable, therapeutic degree of gliosis stimulus. Caution is advised, however, to avoid excessive, prolonged, unsuccessful attempts at ILM peeling, which may harm final visual outcome.

Original languageEnglish (US)
Pages (from-to)304-308
Number of pages5
JournalOphthalmic Practice
Issue number7
StatePublished - 2001

ASJC Scopus subject areas

  • Ophthalmology


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