Interactions between 'handling' and acrylamide on endocrine responses in rats

L. L. Uphouse; C. B. Nemeroff; G. Mason; A. J. Prange; S. C. Bondy

Interactions between 'handling' and acrylamide on endocrine responses in rats

L. L. Uphouse, C. B. Nemeroff, G. Mason, A. J. Prange, S. C. Bondy

Research output: Contribution to journal › Article › peer-review

Abstract

Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and that had been exposed to 100 mg/kg acrylamide. Handling reduced both corticosterone and prolactin levels. Acrylamide had no effect on corticosterone levels. Prolactin levels were significantly lower in acrylamide-exposed nonhandled animals. These findings are discussed in terms of their implications for studying the effects of toxicants on neural function.

Original language	English (US)
Pages (from-to)	121-125
Number of pages	5
Journal	Neurotoxicology
Volume	3
Issue number	1
State	Published - Oct 25 1982
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)
Toxicology

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abstract = "Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and that had been exposed to 100 mg/kg acrylamide. Handling reduced both corticosterone and prolactin levels. Acrylamide had no effect on corticosterone levels. Prolactin levels were significantly lower in acrylamide-exposed nonhandled animals. These findings are discussed in terms of their implications for studying the effects of toxicants on neural function.",

author = "Uphouse, {L. L.} and Nemeroff, {C. B.} and G. Mason and Prange, {A. J.} and Bondy, {S. C.}",

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AU - Nemeroff, C. B.

AU - Mason, G.

AU - Prange, A. J.

AU - Bondy, S. C.

PY - 1982/10/25

Y1 - 1982/10/25

N2 - Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and that had been exposed to 100 mg/kg acrylamide. Handling reduced both corticosterone and prolactin levels. Acrylamide had no effect on corticosterone levels. Prolactin levels were significantly lower in acrylamide-exposed nonhandled animals. These findings are discussed in terms of their implications for studying the effects of toxicants on neural function.

AB - Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and that had been exposed to 100 mg/kg acrylamide. Handling reduced both corticosterone and prolactin levels. Acrylamide had no effect on corticosterone levels. Prolactin levels were significantly lower in acrylamide-exposed nonhandled animals. These findings are discussed in terms of their implications for studying the effects of toxicants on neural function.

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