Intensity-modulated radiotherapy for early glottic cancer: Transition to a new standard of care?

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

For decades, the standard of care for radiation treatment of early larynx cancers has been conventional treatment using opposed lateral fields encompassing the larynx and overlying neck structures, including the adjacent carotid arteries. While intensity-modulated radiotherapy (IMRT) has replaced conventional radiotherapy for all other head/neck cancer situations, the use of IMRT to treat early glottic cancers remains controversial. The article reviews the published experience with IMRT for this clinical situation and provides a detailed review of the literature on radiation-induced carotid toxicity and how it might apply to the controversy. Finally, we discuss whether the radiation oncology community should transition to IMRT as a new standard of care for the treatment of early glottic cancers.

Original languageEnglish (US)
Pages (from-to)2615-2630
Number of pages16
JournalFuture Oncology
Volume12
Issue number22
DOIs
StatePublished - Nov 1 2016

Fingerprint

Tongue Neoplasms
Intensity-Modulated Radiotherapy
Standard of Care
Radiation
Radiation Oncology
Laryngeal Neoplasms
Head and Neck Neoplasms
Larynx
Carotid Arteries
Neck
Radiotherapy
Therapeutics

Keywords

  • carotid injury
  • cerebrovascular
  • glottis
  • IMRT
  • intima
  • larynx
  • radiation
  • stroke

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Intensity-modulated radiotherapy for early glottic cancer : Transition to a new standard of care? / Samuels, Michael A; Freedman, Laura; Elsayyad, Nagy.

In: Future Oncology, Vol. 12, No. 22, 01.11.2016, p. 2615-2630.

Research output: Contribution to journalReview article

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