Intake of plant foods and associated nutrients in prostate cancer risk

John E. Lewis, Hosanna Soler-Vilá, Peter E. Clark, Laura A. Kresty, Glenn O. Allen, Jennifer J. Hu

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42 Scopus citations

Abstract

Plant foods and associated nutrients may impact prostate cancer (PC) risk and survival. Therefore, we compared dietary intake, mainly plant food groups among 382 controls and 478 PC cases (373 incident and 105 prevalent cases). Caucasian controls had significantly higher daily servings of vegetables (3.4 vs. 2.5, P= 0.002) and fruits and/or fruit juices (1.6 vs. 1.3, P = 0.02) compared to African American controls. In Caucasians, incident cases reported lower intake of fiber, vitamin C, vitamin A, α-carotene, β-carotene, cryptoxanthin, folate, genistein, daidzein, and fruits and/or fruit juice than controls and/or prevalent cases. In African Americans, incident cases had lower intake of α-carotene compared to controls and prevalent cases. Reduced PC risk was associated with the highest tertile of cryptoxanthin (OR = 0.51; 95% CI = 0.35-0.75), fiber (OR = 0.56; 95% CI = 0.35-0.89), vitamin C (OR = 0.60; 95% CI = 0.41-0.88), and fruits and/or fruit juices (OR = 0.46; 95% CI = 0.31-0.68), with significant linear trends. Increased risk of PC was associated with the highest tertile of protein (OR = 1.99; 95% CI = 1.05-3.79) and daily servings of grains (OR = 1.99; 95% CI = 1.23-3.22) with significant linear trends. In summary, we demonstrate racial/ethnic differences in dietary intake of plant foods. The significantly higher consumption of protective dietary constituents among prevalent cases compared to incident cases suggests that PC survivors may be amenable to dietary change.

Original languageEnglish (US)
Pages (from-to)216-224
Number of pages9
JournalNutrition and cancer
Volume61
Issue number2
DOIs
StatePublished - Mar 1 2009

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ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Oncology
  • Nutrition and Dietetics
  • Cancer Research

Cite this

Lewis, J. E., Soler-Vilá, H., Clark, P. E., Kresty, L. A., Allen, G. O., & Hu, J. J. (2009). Intake of plant foods and associated nutrients in prostate cancer risk. Nutrition and cancer, 61(2), 216-224. https://doi.org/10.1080/01635580802419756