Insulin, health behaviors, and lipid metabolism

Barbara V. Howard, Neil Schneiderman, Bonita Falkner, Steven M. Haffner, Ami Laws

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Nearly a half century ago, the Framingham Study identified cigarette smoking, high blood pressure, elevated serum cholesterol, and advancing age as risk factors for coronary heart disease (CHD).1 Unfortunately, knowledge about these risk factors, either alone or in combination, does not predict most new cases of CHD. This has led to investigation of other presumed risk factors including diabetes mellitus,2 obesity,3 physical inactivity,4 and such psychosocial variables as type A behavior pattern5 and hostility.6. The association between diabetes mellitus and atherosclerosis in several epidemiological studies7-9 focused attention on the possible role of insulin as a mediating variable. Subsequent prospective studies have linked elevated insulin concentration in the blood of nondiabetic individuals to an increased incidence of myocardial infarction and CHD. Although the exact manner by which insulin metabolism is related to atherosclerosis is not understood, its known relationships to diabetes mellitus, obesity, and physical inactivity make it a prime candidate for study. The focus of this report is on how insulin metabolism may be an important variable linking health behaviors and lipid metabolism.

Original languageEnglish
Pages (from-to)25-35
Number of pages11
JournalMetabolism
Volume42
Issue number9 SUPPL. 1
DOIs
StatePublished - Jan 1 1993

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Health Behavior
Lipid Metabolism
Insulin
Coronary Disease
Diabetes Mellitus
Atherosclerosis
Obesity
Hypercholesterolemia
Smoking
Myocardial Infarction
Prospective Studies
Hypertension
Incidence
Serum

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Howard, B. V., Schneiderman, N., Falkner, B., Haffner, S. M., & Laws, A. (1993). Insulin, health behaviors, and lipid metabolism. Metabolism, 42(9 SUPPL. 1), 25-35. https://doi.org/10.1016/0026-0495(93)90257-O

Insulin, health behaviors, and lipid metabolism. / Howard, Barbara V.; Schneiderman, Neil; Falkner, Bonita; Haffner, Steven M.; Laws, Ami.

In: Metabolism, Vol. 42, No. 9 SUPPL. 1, 01.01.1993, p. 25-35.

Research output: Contribution to journalArticle

Howard, BV, Schneiderman, N, Falkner, B, Haffner, SM & Laws, A 1993, 'Insulin, health behaviors, and lipid metabolism', Metabolism, vol. 42, no. 9 SUPPL. 1, pp. 25-35. https://doi.org/10.1016/0026-0495(93)90257-O
Howard BV, Schneiderman N, Falkner B, Haffner SM, Laws A. Insulin, health behaviors, and lipid metabolism. Metabolism. 1993 Jan 1;42(9 SUPPL. 1):25-35. https://doi.org/10.1016/0026-0495(93)90257-O
Howard, Barbara V. ; Schneiderman, Neil ; Falkner, Bonita ; Haffner, Steven M. ; Laws, Ami. / Insulin, health behaviors, and lipid metabolism. In: Metabolism. 1993 ; Vol. 42, No. 9 SUPPL. 1. pp. 25-35.
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