Insomnia symptoms in South Florida military veterans with epilepsy

M. R. Lopez, J. Y. Cheng, A. M. Kanner, D. Z. Carvalho, J. A. Diamond, D. M. Wallace

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background: Despite the high prevalence of insomnia in veterans with epilepsy, it remains understudied. Our aim was to identify the associations of insomnia with epilepsy, comorbidities, and treatment-related variables in South Florida veterans. Methods: We performed a cross-sectional analysis of veterans attending an epilepsy clinic over 18. months. Participants completed standardized assessments of seizure and sleep. Insomnia was defined as 1) difficulty with sleep onset, maintenance, or premature awakenings with daytime consequences or 2) sedative-hypnotic use on most nights of the previous month. Results: One hundred sixty-five veterans (87% male, age 56 ± 15. years) were included: 66 reporting insomnia (40%). In logistic regression analysis, insomnia was significantly associated with post-traumatic seizure etiology, lamotrigine prescription, and mood and psychotic disorders. Female gender and levetiracetam treatment were associated with lower odds for insomnia. Conclusion: Insomnia was associated with post-traumatic epilepsy, mood/psychotic comorbidities, and antiepileptic regimen. Insomnia represents an under-recognized opportunity to improve comprehensive epilepsy care.

Original languageEnglish (US)
Pages (from-to)159-164
Number of pages6
JournalEpilepsy and Behavior
Issue number1
StatePublished - Apr 2013


  • Epilepsy
  • Insomnia
  • Lamotrigine
  • Levetiracetam
  • Post-traumatic epilepsy
  • Sleep disturbances
  • Veterans

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology


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