Insomnia symptoms in South Florida military veterans with epilepsy

M. R. Lopez, J. Y. Cheng, Andres M Kanner, D. Z. Carvalho, J. A. Diamond, Douglas Wallace

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Despite the high prevalence of insomnia in veterans with epilepsy, it remains understudied. Our aim was to identify the associations of insomnia with epilepsy, comorbidities, and treatment-related variables in South Florida veterans. Methods: We performed a cross-sectional analysis of veterans attending an epilepsy clinic over 18. months. Participants completed standardized assessments of seizure and sleep. Insomnia was defined as 1) difficulty with sleep onset, maintenance, or premature awakenings with daytime consequences or 2) sedative-hypnotic use on most nights of the previous month. Results: One hundred sixty-five veterans (87% male, age 56 ± 15. years) were included: 66 reporting insomnia (40%). In logistic regression analysis, insomnia was significantly associated with post-traumatic seizure etiology, lamotrigine prescription, and mood and psychotic disorders. Female gender and levetiracetam treatment were associated with lower odds for insomnia. Conclusion: Insomnia was associated with post-traumatic epilepsy, mood/psychotic comorbidities, and antiepileptic regimen. Insomnia represents an under-recognized opportunity to improve comprehensive epilepsy care.

Original languageEnglish
Pages (from-to)159-164
Number of pages6
JournalEpilepsy and Behavior
Volume27
Issue number1
DOIs
StatePublished - Apr 1 2013

Fingerprint

Sleep Initiation and Maintenance Disorders
Veterans
Epilepsy
etiracetam
Comorbidity
Sleep
Seizures
Post-Traumatic Epilepsy
Psychotic Affective Disorders
Hypnotics and Sedatives
Anticonvulsants
Prescriptions
Cross-Sectional Studies
Logistic Models
Regression Analysis
Maintenance
Therapeutics

Keywords

  • Epilepsy
  • Insomnia
  • Lamotrigine
  • Levetiracetam
  • Post-traumatic epilepsy
  • Sleep disturbances
  • Veterans

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

Insomnia symptoms in South Florida military veterans with epilepsy. / Lopez, M. R.; Cheng, J. Y.; Kanner, Andres M; Carvalho, D. Z.; Diamond, J. A.; Wallace, Douglas.

In: Epilepsy and Behavior, Vol. 27, No. 1, 01.04.2013, p. 159-164.

Research output: Contribution to journalArticle

Lopez, M. R. ; Cheng, J. Y. ; Kanner, Andres M ; Carvalho, D. Z. ; Diamond, J. A. ; Wallace, Douglas. / Insomnia symptoms in South Florida military veterans with epilepsy. In: Epilepsy and Behavior. 2013 ; Vol. 27, No. 1. pp. 159-164.
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