Abstract
Background: There is limited data on chronic insomnia in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans, in whom post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) often co-exist. Our aim was to compare sleep characteristics of three groups of OEF/OIF veterans: (1) healthy sleepers (HS), (2) those with insomnia associated with PTSD and mTBI (PTSD-mTBI), and (3) those with insomnia associated with PTSD alone. Methods: Consecutive veterans with insomnia complaints (>6 months) were recruited over 6 months from the Miami VA Post Deployment clinic. Participants completed a sleep disorders clinical interview, medical history, and questionnaires about insomnia, sleepiness, pain, fatigue, depression, PTSD, and health-related quality of life. They underwent polysomnography (PSG) with 2 weeks of actigraphy (ACT) and sleep diaries. Results: There were no differences in demographics or most questionnaire responses between PTSD and PTSD-mTBI groups. Subjective daytime sleepiness was significantly greater in PTSD-mTBI subjects compared with HS and PTSD participants. Significant co-morbid sleep disorders were noted in insomnia patients. PSG and ACT wake after sleep onset was significantly shorter in PTSD-mTBI subjects as compared with PTSD participants. Conclusion: Insomnia patients with PTSD-mTBI were subjectively sleepier despite spending less time awake during the night than PTSD subjects, possibly as a consequence of head trauma.
| Original language | English |
|---|---|
| Pages (from-to) | 850-859 |
| Number of pages | 10 |
| Journal | Sleep Medicine |
| Volume | 12 |
| Issue number | 9 |
| DOIs | |
| State | Published - Oct 1 2011 |
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Keywords
- Actigraphy
- Insomnia
- Post-traumatic stress disorder
- Sleep disturbances
- Traumatic brain injury
- Veterans
ASJC Scopus subject areas
- Medicine(all)
Cite this
Insomnia characteristics and clinical correlates in Operation Enduring Freedom/Operation Iraqi Freedom veterans with post-traumatic stress disorder and mild traumatic brain injury : An exploratory study. / Wallace, Douglas; Shafazand, Shirin; Ramos, Alberto; Carvalho, D. Z.; Gardener, H.; Lorenzo, D.; Wohlgemuth, W. K.
In: Sleep Medicine, Vol. 12, No. 9, 01.10.2011, p. 850-859.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Insomnia characteristics and clinical correlates in Operation Enduring Freedom/Operation Iraqi Freedom veterans with post-traumatic stress disorder and mild traumatic brain injury
T2 - An exploratory study
AU - Wallace, Douglas
AU - Shafazand, Shirin
AU - Ramos, Alberto
AU - Carvalho, D. Z.
AU - Gardener, H.
AU - Lorenzo, D.
AU - Wohlgemuth, W. K.
PY - 2011/10/1
Y1 - 2011/10/1
N2 - Background: There is limited data on chronic insomnia in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans, in whom post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) often co-exist. Our aim was to compare sleep characteristics of three groups of OEF/OIF veterans: (1) healthy sleepers (HS), (2) those with insomnia associated with PTSD and mTBI (PTSD-mTBI), and (3) those with insomnia associated with PTSD alone. Methods: Consecutive veterans with insomnia complaints (>6 months) were recruited over 6 months from the Miami VA Post Deployment clinic. Participants completed a sleep disorders clinical interview, medical history, and questionnaires about insomnia, sleepiness, pain, fatigue, depression, PTSD, and health-related quality of life. They underwent polysomnography (PSG) with 2 weeks of actigraphy (ACT) and sleep diaries. Results: There were no differences in demographics or most questionnaire responses between PTSD and PTSD-mTBI groups. Subjective daytime sleepiness was significantly greater in PTSD-mTBI subjects compared with HS and PTSD participants. Significant co-morbid sleep disorders were noted in insomnia patients. PSG and ACT wake after sleep onset was significantly shorter in PTSD-mTBI subjects as compared with PTSD participants. Conclusion: Insomnia patients with PTSD-mTBI were subjectively sleepier despite spending less time awake during the night than PTSD subjects, possibly as a consequence of head trauma.
AB - Background: There is limited data on chronic insomnia in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans, in whom post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) often co-exist. Our aim was to compare sleep characteristics of three groups of OEF/OIF veterans: (1) healthy sleepers (HS), (2) those with insomnia associated with PTSD and mTBI (PTSD-mTBI), and (3) those with insomnia associated with PTSD alone. Methods: Consecutive veterans with insomnia complaints (>6 months) were recruited over 6 months from the Miami VA Post Deployment clinic. Participants completed a sleep disorders clinical interview, medical history, and questionnaires about insomnia, sleepiness, pain, fatigue, depression, PTSD, and health-related quality of life. They underwent polysomnography (PSG) with 2 weeks of actigraphy (ACT) and sleep diaries. Results: There were no differences in demographics or most questionnaire responses between PTSD and PTSD-mTBI groups. Subjective daytime sleepiness was significantly greater in PTSD-mTBI subjects compared with HS and PTSD participants. Significant co-morbid sleep disorders were noted in insomnia patients. PSG and ACT wake after sleep onset was significantly shorter in PTSD-mTBI subjects as compared with PTSD participants. Conclusion: Insomnia patients with PTSD-mTBI were subjectively sleepier despite spending less time awake during the night than PTSD subjects, possibly as a consequence of head trauma.
KW - Actigraphy
KW - Insomnia
KW - Post-traumatic stress disorder
KW - Sleep disturbances
KW - Traumatic brain injury
KW - Veterans
UR - http://www.scopus.com/inward/record.url?scp=80455174578&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80455174578&partnerID=8YFLogxK
U2 - 10.1016/j.sleep.2011.06.004
DO - 10.1016/j.sleep.2011.06.004
M3 - Article
C2 - 21925943
AN - SCOPUS:80455174578
VL - 12
SP - 850
EP - 859
JO - Sleep Medicine
JF - Sleep Medicine
SN - 1389-9457
IS - 9
ER -