Initial levels of CEA and their rate of change in pancreatic carcinoma following surgery chemotherapy and radiation therapy

J. S. Barkin, M. H. Kalser, R. Kaplan, D. Redlhammer, A. Heal

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

CEA levels and their rate of change in 41 patients with pancreatic carcinoma following surgery, chemotherapy and radiation therapy were determined. Surgical resection, though not curative, was associated with a decrease in CEA level, with approximately half these levels returned to normal. No correlation with survival was noted. CEA levels are increased by obstructive jaundice. Radiation alone or in combination with 5-Fluorouracil did not not change CEA levels in patients with locally unresectable pancreatic carcinoma. CEA levels progressively increased in patients with widespread metastatic pancreatic carcinoma, who expired from their disease.

Original languageEnglish (US)
Pages (from-to)1472-1476
Number of pages5
JournalCancer
Volume42
Issue number3 S
DOIs
StatePublished - Sep 1978

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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