Inhibition of release in the baboon by inhibitory analogs of luteinizing hormone releasing hormone

Hagino; D. H. Coy; A. V. Schally; A. Arimura

doi:10.1055/s-0028-1095559

Inhibition of release in the baboon by inhibitory analogs of luteinizing hormone releasing hormone

Hagino, D. H. Coy, A. V. Schally, A. Arimura

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Three normally cycling female baboons in the luteal phase were selected to determine the suppressing effect of Inhibitor-I: D-phe2, phe3, D-phe6-LHRH, on LH release in response to synthetic LHRH. The results support the interpretation that Inhibitor-I suppresses the function of LHRH, however, there is not yet enough evidence to state that Inhibitor-I suppresses endogenous LHRH secretion rather than suppressing the activity of endogenous LHRH at the level of the anterior pituitary.

Original language	English (US)
Pages (from-to)	247-248
Number of pages	2
Journal	Hormone and Metabolic Research
Volume	9
Issue number	3
DOIs	https://doi.org/10.1055/s-0028-1095559
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

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title = "Inhibition of release in the baboon by inhibitory analogs of luteinizing hormone releasing hormone",

abstract = "Three normally cycling female baboons in the luteal phase were selected to determine the suppressing effect of Inhibitor-I: D-phe2, phe3, D-phe6-LHRH, on LH release in response to synthetic LHRH. The results support the interpretation that Inhibitor-I suppresses the function of LHRH, however, there is not yet enough evidence to state that Inhibitor-I suppresses endogenous LHRH secretion rather than suppressing the activity of endogenous LHRH at the level of the anterior pituitary.",

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year = "1977",

doi = "10.1055/s-0028-1095559",

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AU - Hagino,

AU - Coy, D. H.

AU - Schally, A. V.

AU - Arimura, A.

PY - 1977

Y1 - 1977

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AB - Three normally cycling female baboons in the luteal phase were selected to determine the suppressing effect of Inhibitor-I: D-phe2, phe3, D-phe6-LHRH, on LH release in response to synthetic LHRH. The results support the interpretation that Inhibitor-I suppresses the function of LHRH, however, there is not yet enough evidence to state that Inhibitor-I suppresses endogenous LHRH secretion rather than suppressing the activity of endogenous LHRH at the level of the anterior pituitary.

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