Melanogenesis generates immunosuppressive and mutagenic environment and alters cellular metabolism. Melanin can protect malignant melanocytes against chemo-, radio-, and photodynamic therapy. Therefore, we propose to inhibit melanogenesis as an adjuvant treatment modality during immuno-, radio-, chemo- and photodynamic therapy, and as a measure of reducing the probability of melanoma progression.
|Original language||English (US)|
|Number of pages||7|
|Issue number||5 B|
|State||Published - Sep 1 1998|
ASJC Scopus subject areas
- Cancer Research