Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat

Claus Peter Richter, Suhrud M Rajguru, Alan Robinson, Hunter K. Young

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Infrared neural stimulation (INS) has been used in the past to evoke neural activity from hearing and partially deaf animals. All the responses were excitatory. In Aplysia californica, Duke and coworkers demonstrated that INS also inhibits neural responses [1], which similar observations were made in the vestibular system [2, 3]. In deaf white cats that have cochleae with largely reduced spiral ganglion neuron counts and a significant degeneration of the organ of Corti, no cochlear compound action potentials could be observed during INS alone. However, the combined electrical and optical stimulation demonstrated inhibitory responses during irradiation with infrared light.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume8928
ISBN (Print)9780819498410
DOIs
StatePublished - Jan 1 2014
EventOptical Techniques in Neurosurgery, Neurophotonics, and Optogenetics - San Francisco, CA, United States
Duration: Feb 1 2014Feb 4 2014

Other

OtherOptical Techniques in Neurosurgery, Neurophotonics, and Optogenetics
CountryUnited States
CitySan Francisco, CA
Period2/1/142/4/14

Fingerprint

cats
Cochlea
stimulation
Cats
Spiral Ganglion
Infrared radiation
Organ of Corti
Aplysia
Electric Stimulation
Hearing
Action Potentials
Neurons
Light
cochlea
degeneration
Audition
hearing
neurons
organs
animals

Keywords

  • cochlea
  • hearing
  • infrared neural stimulation
  • inhibition
  • laser

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Richter, C. P., Rajguru, S. M., Robinson, A., & Young, H. K. (2014). Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8928). [892818] SPIE. https://doi.org/10.1117/12.2049322

Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat. / Richter, Claus Peter; Rajguru, Suhrud M; Robinson, Alan; Young, Hunter K.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8928 SPIE, 2014. 892818.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Richter, CP, Rajguru, SM, Robinson, A & Young, HK 2014, Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8928, 892818, SPIE, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, San Francisco, CA, United States, 2/1/14. https://doi.org/10.1117/12.2049322
Richter CP, Rajguru SM, Robinson A, Young HK. Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8928. SPIE. 2014. 892818 https://doi.org/10.1117/12.2049322
Richter, Claus Peter ; Rajguru, Suhrud M ; Robinson, Alan ; Young, Hunter K. / Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8928 SPIE, 2014.
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