Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat

Claus Peter Richter, Suhrud M. Rajguru, Alan Robinson, Hunter K. Young

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Infrared neural stimulation (INS) has been used in the past to evoke neural activity from hearing and partially deaf animals. All the responses were excitatory. In Aplysia californica, Duke and coworkers demonstrated that INS also inhibits neural responses [1], which similar observations were made in the vestibular system [2, 3]. In deaf white cats that have cochleae with largely reduced spiral ganglion neuron counts and a significant degeneration of the organ of Corti, no cochlear compound action potentials could be observed during INS alone. However, the combined electrical and optical stimulation demonstrated inhibitory responses during irradiation with infrared light.

Original languageEnglish (US)
Title of host publicationOptical Techniques in Neurosurgery, Neurophotonics, and Optogenetics
PublisherSPIE
ISBN (Print)9780819498410
DOIs
StatePublished - Jan 1 2014
EventOptical Techniques in Neurosurgery, Neurophotonics, and Optogenetics - San Francisco, CA, United States
Duration: Feb 1 2014Feb 4 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8928
ISSN (Print)1605-7422

Other

OtherOptical Techniques in Neurosurgery, Neurophotonics, and Optogenetics
CountryUnited States
CitySan Francisco, CA
Period2/1/142/4/14

Keywords

  • cochlea
  • hearing
  • infrared neural stimulation
  • inhibition
  • laser

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat'. Together they form a unique fingerprint.

Cite this