Infrared neural stimulation in the cochlea

Claus Peter Richter, Suhrud M Rajguru, Mark Bendett

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)

Abstract

The application of photonics to manipulate and stimulate neurons and to study neural networks has gained momentum over the last decade. Two general methods have been used: the genetic expression of light or temperature sensitive ion channels in the plasma membrane of neurons (Optogenetics and Thermogenetics) and the direct stimulation of neurons using infrared radiation (Infrared Neural Stimulation, INS). Both approaches have their strengths and challenges, which are well understood with a profound understanding of the light tissue interaction(s). This paper compares the opportunities of the methods for the use in cochlear prostheses. Ample data are already available on the stimulation of the cochlea with INS. The data show that the stimulation is selective, feasible at rates that would be sufficient to encode acoustic information and may be beneficial over conventional pulsed electrical stimulation. A third approach, using lasers in stress confinement to generate pressure waves and to stimulate the functional cochlea mechanically will also be discussed.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
DOIs
StatePublished - May 30 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period2/2/132/7/13

Fingerprint

cochlea
Cochlea
stimulation
Neurons
Infrared radiation
Optogenetics
neurons
Optics and Photonics
Light
Cochlear Implants
Cell membranes
Prosthetics
Ion Channels
Acoustics
Photonics
Electric Stimulation
Momentum
Lasers
Cell Membrane
Radiation

Keywords

  • Cochlear implants
  • Infrared neural stimulation
  • Optical stimulation
  • Optogenetics
  • Thermogenetics

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Richter, C. P., Rajguru, S. M., & Bendett, M. (2013). Infrared neural stimulation in the cochlea. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8565). [85651Y] https://doi.org/10.1117/12.2010337

Infrared neural stimulation in the cochlea. / Richter, Claus Peter; Rajguru, Suhrud M; Bendett, Mark.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013. 85651Y.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Richter, CP, Rajguru, SM & Bendett, M 2013, Infrared neural stimulation in the cochlea. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8565, 85651Y, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, United States, 2/2/13. https://doi.org/10.1117/12.2010337
Richter CP, Rajguru SM, Bendett M. Infrared neural stimulation in the cochlea. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565. 2013. 85651Y https://doi.org/10.1117/12.2010337
Richter, Claus Peter ; Rajguru, Suhrud M ; Bendett, Mark. / Infrared neural stimulation in the cochlea. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013.
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