TY - GEN
T1 - Information theoretical estimators of tuning depth and time delay for motor cortex neurons
AU - Wang, Yiwen
AU - Sanchez, Justin C.
AU - Principe, Jose C.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - Knowledge of neural receptive fields helps decode animal's movement from neural activity in motor brain machine interfaces (BMI). The traditional tuning depth is a coarse metric to evaluate the neuron's tuning properties. The major difficulty of the tuning depth is that it does not allow for a direct comparison among neurons that have very different firing rates. An information theoretic tuning depth based on mutual information is proposed to evaluate how neural spikes encode the kinematic direction. This metric is scale invariant and makes the tuning analysis comparable among not only the cortical areas but also among kinematics vectors. It can help identify candidate neuron subsets to reduce the complexity of analysis and decoding in BMI. The application of the metric on neural encoding modeling also provides a way to estimate time delays in motor cortical neural activity.
AB - Knowledge of neural receptive fields helps decode animal's movement from neural activity in motor brain machine interfaces (BMI). The traditional tuning depth is a coarse metric to evaluate the neuron's tuning properties. The major difficulty of the tuning depth is that it does not allow for a direct comparison among neurons that have very different firing rates. An information theoretic tuning depth based on mutual information is proposed to evaluate how neural spikes encode the kinematic direction. This metric is scale invariant and makes the tuning analysis comparable among not only the cortical areas but also among kinematics vectors. It can help identify candidate neuron subsets to reduce the complexity of analysis and decoding in BMI. The application of the metric on neural encoding modeling also provides a way to estimate time delays in motor cortical neural activity.
UR - http://www.scopus.com/inward/record.url?scp=34548763788&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548763788&partnerID=8YFLogxK
U2 - 10.1109/CNE.2007.369719
DO - 10.1109/CNE.2007.369719
M3 - Conference contribution
AN - SCOPUS:34548763788
SN - 1424407923
SN - 9781424407927
T3 - Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering
SP - 502
EP - 505
BT - Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering
T2 - 3rd International IEEE EMBS Conference on Neural Engineering
Y2 - 2 May 2007 through 5 May 2007
ER -