Influencing medication adherence among women with AIDS

Deborah Jones, M. Ishii, A. LaPerriere, Heidi Allespach, Michael H Antoni, Gail Ironson, Neil Schneiderman, F. Van Splunteren, A. Cassells, K. Alexander, Y. P. Gousse, A. Vaughn, E. Brondolo, J. N. Tobin, Stephen M Weiss

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

This study examined the effects of a ten-session cognitive-behavioural stress management/expressive supportive therapy (CBSM+) intervention on adherence to antiretroviral medication. Although the intervention was not designed to influence adherence, it was theorized that improved coping and social support could enhance adherence. Women with AIDS (N = 174) in Miami, New York and New Jersey, USA, were randomized to a group CBSM+ intervention or individual control condition. Participants were African American (55%), Latina (18%) and Caribbean (18%) with drug (55%) and/or alcohol (32%) histories. Participants were assessed on self-reported medication adherence over seven days, HIV-related coping strategies and beliefs regarding HIV medication. Baseline overall self-reported adherence rates were moderate and related to coping strategies and HIV medication beliefs. Low adherent (80%) participants in the intervention condition increased their mean self-reported medication adherence (30.4% increase, t44 = 3.1, p < 0.01), whereas low adherent women in the control condition showed a non-significant trend (19.6% increase, t44 = 2.0, p > 0.05). The intervention did not improve adherence in this population; conditions did not differ significantly on self-reported adherence. Low adhering intervention participants significantly decreased levels of denial-based coping (F1,88 = 5.97, p < 0.05). Results suggest that future interventions should utilize group formats and address adherence using coping and medication-knowledge focused strategies.

Original languageEnglish
Pages (from-to)463-474
Number of pages12
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume15
Issue number4
DOIs
StatePublished - Aug 1 2003
Externally publishedYes

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Medication Adherence
Acquired Immunodeficiency Syndrome
AIDS
medication
HIV
coping
self-medication
Hispanic Americans
Social Support
African Americans
Alcohols
stress management
Pharmaceutical Preparations
Population
social support
Group
alcohol
drug
Therapeutics
history

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Health Professions(all)
  • Social Sciences (miscellaneous)

Cite this

Influencing medication adherence among women with AIDS. / Jones, Deborah; Ishii, M.; LaPerriere, A.; Allespach, Heidi; Antoni, Michael H; Ironson, Gail; Schneiderman, Neil; Van Splunteren, F.; Cassells, A.; Alexander, K.; Gousse, Y. P.; Vaughn, A.; Brondolo, E.; Tobin, J. N.; Weiss, Stephen M.

In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 15, No. 4, 01.08.2003, p. 463-474.

Research output: Contribution to journalArticle

Jones, D, Ishii, M, LaPerriere, A, Allespach, H, Antoni, MH, Ironson, G, Schneiderman, N, Van Splunteren, F, Cassells, A, Alexander, K, Gousse, YP, Vaughn, A, Brondolo, E, Tobin, JN & Weiss, SM 2003, 'Influencing medication adherence among women with AIDS', AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, vol. 15, no. 4, pp. 463-474. https://doi.org/10.1080/0954012031000134700
Jones, Deborah ; Ishii, M. ; LaPerriere, A. ; Allespach, Heidi ; Antoni, Michael H ; Ironson, Gail ; Schneiderman, Neil ; Van Splunteren, F. ; Cassells, A. ; Alexander, K. ; Gousse, Y. P. ; Vaughn, A. ; Brondolo, E. ; Tobin, J. N. ; Weiss, Stephen M. / Influencing medication adherence among women with AIDS. In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 2003 ; Vol. 15, No. 4. pp. 463-474.
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