Influence of oestrous cyclicity on some aspects of carbohydrate metabolism of the submandibular salivary gland of the albino rat

P. M. Ambadkar, S. J. Killedar, Ami Raval

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Titres of oestrogen are known to rise from dioestrous to proestrous stage of the oestrous cycle. Such a rising level of estrogen may be responsible for rise in intracellular concentration of cAMP. The estrogen primed tissue, changing from proestrous to oestrous, under known increasing progesterone level and preovulatory LH surge, may led to a sort of balancing action on the varying levels of glycogen synthetase and phosphorylase enzyme activities so as to play a role in maintaining a steady state of glycogen concentration in the salivary gland. Therefore, alterations in glycogen concentration and the activities of concerned enzymes viz. glycogen synthetase, phosphorylase and cAMP-specific phosphodiesterase (cAMP-PDE) have been studied in albino rats. An abrupt but significant drop in cAMP-specific phosphodiesterase (cAMP-PDE) activity was found to facilitate corresponding reduction in glycogen and lowering protein concentration of the gland, during transition from oestrous to metoestrous. Main features of the meteostrous stage were depletion of glycogen and protein concentration. Taking into consideration the alteration of glandular glycogen and protein concentration, during various stages of oestrous cycle, variation in the viscosity of saliva has been suggested; in phase with the cyclicity.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalIndian Journal of Experimental Biology
Volume32
Issue number2
StatePublished - Jan 1 1994
Externally publishedYes

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Submandibular Gland
Carbohydrate Metabolism
Periodicity
Salivary Glands
Glycogen
Rats
Glycogen Phosphorylase
Glycogen Synthase
Estrogens
Phosphoric Diester Hydrolases
Proteins
Phosphorylases
Enzyme activity
Enzymes
Saliva
Viscosity
Progesterone
Tissue

ASJC Scopus subject areas

  • Bioengineering

Cite this

Influence of oestrous cyclicity on some aspects of carbohydrate metabolism of the submandibular salivary gland of the albino rat. / Ambadkar, P. M.; Killedar, S. J.; Raval, Ami.

In: Indian Journal of Experimental Biology, Vol. 32, No. 2, 01.01.1994, p. 89-91.

Research output: Contribution to journalArticle

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