Inflammation in osteoarthritis

The inflammation present in OA is irrespective of whether OA is without known cause (idiopathic) or associated with another illness (secondary). In erosive OA, synovitis of mild to moderate severity is a common manifestation of primary generalized (polyarticular) OA. In the following, we review the clinical, biochemical, histological and other aspects of the inflammatory process in OA with emphasis on the coexistence of inflammation.