Infectious morbidity in gynecologic cancer

Doris C. Brooker; John E. Savage; Leo B. Twiggs; Leon L. Adcock; Konald A. Prem; Christine C. Sanders

doi:10.1016/0002-9378(87)90322-X

Infectious morbidity in gynecologic cancer

Doris C. Brooker, John E. Savage, Leo B. Twiggs, Leon L. Adcock, Konald A. Prem, Christine C. Sanders

Research output: Contribution to journal › Article

9 Scopus citations

Abstract

A retrospective investigation of infectious morbidity in gynecologic oncology patients documented that 54 (11%) of 494 patients and 68 (6%) of 1204 patient admissions were complicated by a serious infection. The highest rate of infectious morbidity by admission was 21%, occurring in patients admitted for cancer of the vulva. The highest surgical infectious morbidity, 22%, occurred in patients admitted for cervical cancer. important factors in determining infection risk include multiple host factors, radical surgical procedures, factors inherent in the tumor itself, and additional irradiation and chemotherapy. These serious polymicrobial infections dictate intelligent selection of antimicrobials and appropriate monitoring to anticipate complications inherent in antimicrobial therapy. β-Lactamase induction, superinfection, nephrotoxicity, and necrotizing enterocolitis are documented problems in these patients.

Original language	English
Pages (from-to)	513-520
Number of pages	8
Journal	American Journal of Obstetrics and Gynecology
Volume	156
Issue number	2
DOIs	https://doi.org/10.1016/0002-9378(87)90322-X
State	Published - Jan 1 1987
Externally published	Yes

Fingerprint

Keywords

genital tract malignancy
gynecologic cancer
Infectious morbidity

ASJC Scopus subject areas

Medicine(all)
Obstetrics and Gynecology

Cite this

Brooker, D. C., Savage, J. E., Twiggs, L. B., Adcock, L. L., Prem, K. A., & Sanders, C. C. (1987). Infectious morbidity in gynecologic cancer. American Journal of Obstetrics and Gynecology, 156(2), 513-520. https://doi.org/10.1016/0002-9378(87)90322-X

@article{c42f20517e2241459d7dd159d7ceba51,

title = "Infectious morbidity in gynecologic cancer",

abstract = "A retrospective investigation of infectious morbidity in gynecologic oncology patients documented that 54 (11%) of 494 patients and 68 (6%) of 1204 patient admissions were complicated by a serious infection. The highest rate of infectious morbidity by admission was 21%, occurring in patients admitted for cancer of the vulva. The highest surgical infectious morbidity, 22%, occurred in patients admitted for cervical cancer. important factors in determining infection risk include multiple host factors, radical surgical procedures, factors inherent in the tumor itself, and additional irradiation and chemotherapy. These serious polymicrobial infections dictate intelligent selection of antimicrobials and appropriate monitoring to anticipate complications inherent in antimicrobial therapy. β-Lactamase induction, superinfection, nephrotoxicity, and necrotizing enterocolitis are documented problems in these patients.",

keywords = "genital tract malignancy, gynecologic cancer, Infectious morbidity",

author = "Brooker, {Doris C.} and Savage, {John E.} and Twiggs, {Leo B.} and Adcock, {Leon L.} and Prem, {Konald A.} and Sanders, {Christine C.}",

year = "1987",

month = jan

day = "1",

doi = "10.1016/0002-9378(87)90322-X",

language = "English",

volume = "156",

pages = "513--520",

journal = "American Journal of Obstetrics and Gynecology",

issn = "0002-9378",

publisher = "Mosby Inc.",

number = "2",

}

TY - JOUR

T1 - Infectious morbidity in gynecologic cancer

AU - Brooker, Doris C.

AU - Savage, John E.

AU - Twiggs, Leo B.

AU - Adcock, Leon L.

AU - Prem, Konald A.

AU - Sanders, Christine C.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - A retrospective investigation of infectious morbidity in gynecologic oncology patients documented that 54 (11%) of 494 patients and 68 (6%) of 1204 patient admissions were complicated by a serious infection. The highest rate of infectious morbidity by admission was 21%, occurring in patients admitted for cancer of the vulva. The highest surgical infectious morbidity, 22%, occurred in patients admitted for cervical cancer. important factors in determining infection risk include multiple host factors, radical surgical procedures, factors inherent in the tumor itself, and additional irradiation and chemotherapy. These serious polymicrobial infections dictate intelligent selection of antimicrobials and appropriate monitoring to anticipate complications inherent in antimicrobial therapy. β-Lactamase induction, superinfection, nephrotoxicity, and necrotizing enterocolitis are documented problems in these patients.

AB - A retrospective investigation of infectious morbidity in gynecologic oncology patients documented that 54 (11%) of 494 patients and 68 (6%) of 1204 patient admissions were complicated by a serious infection. The highest rate of infectious morbidity by admission was 21%, occurring in patients admitted for cancer of the vulva. The highest surgical infectious morbidity, 22%, occurred in patients admitted for cervical cancer. important factors in determining infection risk include multiple host factors, radical surgical procedures, factors inherent in the tumor itself, and additional irradiation and chemotherapy. These serious polymicrobial infections dictate intelligent selection of antimicrobials and appropriate monitoring to anticipate complications inherent in antimicrobial therapy. β-Lactamase induction, superinfection, nephrotoxicity, and necrotizing enterocolitis are documented problems in these patients.

KW - genital tract malignancy

KW - gynecologic cancer

KW - Infectious morbidity

UR - http://www.scopus.com/inward/record.url?scp=0023121741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023121741&partnerID=8YFLogxK

U2 - 10.1016/0002-9378(87)90322-X

DO - 10.1016/0002-9378(87)90322-X

M3 - Article

C2 - 3826191

AN - SCOPUS:0023121741

VL - 156

SP - 513

EP - 520

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 2

ER -

Access to Document

10.1016/0002-9378(87)90322-X