Infection rates after 3175 total hip and total knee replacements performed with and without a horizontal unidirectional filtered air-flow system

E. A. Salvati, Raymond Robinson, S. M. Zeno, B. L. Koslin, B. D. Brause, P. D. Wilson

Research output: Contribution to journalArticle

224 Citations (Scopus)

Abstract

To determine the effect of the ventilation system on infection rates after total hip and total knee arthroplasties performed in operating rooms with and without a horizontal unidirectional filtered air-flow system, using modern antiseptic conditions and antibiotic prophylaxis, all of the single-stage procedures (3175 of a total of 4769) were subjected to statistical analysis and fifty-seven matched pairs for controls were established. A reduced infection rate after total hip replacement (from 1.4 to 0.9 per cent) and an increased infection rate after total knee replacement (from 1.4 to 3.9 per cent) were found when patients operated on in the filtered laminar air-flow operating room were compared with those whose operations were done in two conventional rooms. This pattern was statistically significant and was believed to be due to the positions of the operating team and of the wound with respect to the air flow. Prospectively accumulated factors (such as the experience of the surgeon, the duration of surgery, the diagnosis, and the patient's age) as well as retrospectively accumulated factors (such as predisposing conditions of the patient) did not explain the observed patterns of infection.

Original languageEnglish
Pages (from-to)525-535
Number of pages11
JournalJournal of Bone and Joint Surgery - Series A
Volume64
Issue number4
StatePublished - Jul 13 1982
Externally publishedYes

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Knee Replacement Arthroplasties
Hip
Air
Operating Rooms
Infection
Local Anti-Infective Agents
Antibiotic Prophylaxis
Hip Replacement Arthroplasties
Ventilation
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Infection rates after 3175 total hip and total knee replacements performed with and without a horizontal unidirectional filtered air-flow system. / Salvati, E. A.; Robinson, Raymond; Zeno, S. M.; Koslin, B. L.; Brause, B. D.; Wilson, P. D.

In: Journal of Bone and Joint Surgery - Series A, Vol. 64, No. 4, 13.07.1982, p. 525-535.

Research output: Contribution to journalArticle

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