TY - JOUR
T1 - Infantile Myofibromatosis
T2 - A Nontraumatic Cause of Neonatal Brachial Plexus Palsy
AU - Tierney, Travis S.
AU - Tierney, Brent J.
AU - Rosenberg, Andrew E.
AU - Krishnamoorthy, Kalpathy S.
AU - Butler, William E.
PY - 2008/10/1
Y1 - 2008/10/1
N2 - Most injuries to the neonatal brachial plexus occur acutely at birth, and are iatrogenic in origin. However, when weakness is accompanied by atrophy, nontraumatic etiologies should be considered. The differential diagnosis of chronic congenital brachial plexopathy includes cervical bone malformations, humeral osteomyelitis, varicella, and compression from various types of infantile tumors. An illustrative male infant delivered at 37 weeks of gestation with wasted musculature of the left upper arm, ipsilateral Horner's syndrome, and a hemidiaphragm is presented. On further examination, this patient manifested an underlying cervical tumor compressing the brachial plexus. Diagnostic steps leading to the pathologic identification of a solitary cervical myofibroma included physical examination, electromyography, radiographic imaging, and open biopsy. This report emphasizes the importance of differentiating acute from chronic congenital plexus palsy and of recognizing the possibility that infection or neoplasm may underlie the latter.
AB - Most injuries to the neonatal brachial plexus occur acutely at birth, and are iatrogenic in origin. However, when weakness is accompanied by atrophy, nontraumatic etiologies should be considered. The differential diagnosis of chronic congenital brachial plexopathy includes cervical bone malformations, humeral osteomyelitis, varicella, and compression from various types of infantile tumors. An illustrative male infant delivered at 37 weeks of gestation with wasted musculature of the left upper arm, ipsilateral Horner's syndrome, and a hemidiaphragm is presented. On further examination, this patient manifested an underlying cervical tumor compressing the brachial plexus. Diagnostic steps leading to the pathologic identification of a solitary cervical myofibroma included physical examination, electromyography, radiographic imaging, and open biopsy. This report emphasizes the importance of differentiating acute from chronic congenital plexus palsy and of recognizing the possibility that infection or neoplasm may underlie the latter.
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U2 - 10.1016/j.pediatrneurol.2008.06.009
DO - 10.1016/j.pediatrneurol.2008.06.009
M3 - Article
C2 - 18805367
AN - SCOPUS:52049090151
VL - 39
SP - 276
EP - 278
JO - Pediatric Neurology
JF - Pediatric Neurology
SN - 0887-8994
IS - 4
ER -