TY - JOUR
T1 - Infantile Myofibromatosis
T2 - A Case Report
AU - Bellman, Betty
AU - Wooming, George
AU - Landsman, Larry
AU - Penneys, Neal
AU - Schachner, Lawrence A.
PY - 1991/12
Y1 - 1991/12
N2 - A male infant had three nodules on the left cheek, right forearm, and right neck. Biopsy specimen revealed infantile myofibromatosis (IM). Further evaluation revealed a solitary pulmonary nodule in the right middle lobe located far from mediastinal structures, which had no evidence of tumor enlargement on follow-up tomographic scan. Immunoperoxidase studies were negative for desmin and positive for actin. This is a potentially life-threatening multiorgan system disease; however, if lesions are limited mainly to the skin and soft tissues, the prognosis becomes more favorable. Although many reports suggest spontaneous and complete healing of the cutaneous lesions, our patient had profound atrophy at lesion sites as resolution occurred.
AB - A male infant had three nodules on the left cheek, right forearm, and right neck. Biopsy specimen revealed infantile myofibromatosis (IM). Further evaluation revealed a solitary pulmonary nodule in the right middle lobe located far from mediastinal structures, which had no evidence of tumor enlargement on follow-up tomographic scan. Immunoperoxidase studies were negative for desmin and positive for actin. This is a potentially life-threatening multiorgan system disease; however, if lesions are limited mainly to the skin and soft tissues, the prognosis becomes more favorable. Although many reports suggest spontaneous and complete healing of the cutaneous lesions, our patient had profound atrophy at lesion sites as resolution occurred.
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U2 - 10.1111/j.1525-1470.1991.tb00939.x
DO - 10.1111/j.1525-1470.1991.tb00939.x
M3 - Article
C2 - 1792204
AN - SCOPUS:0026319308
VL - 8
SP - 306
EP - 309
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 4
ER -