Induction of labor in the high risk pregnancy with PGF(2α)

M. J. O'Sullivan, M. L. Stone, C. L. Gugliucci, M. E. Stephens

Research output: Contribution to journalArticle

4 Scopus citations


The induction of labor in the high-risk patient is accompanied by an increased incidence of cesarean section partly due to failed induction. A series of 50 high-risk patients induced with intravenous prostaglandin F(2α) is presented. Forty-five were successfully induced, 35 of whom delivered vaginally. Failed inductions occurred in 5 patients. The overall success rate was 90% and cesarean section rate was 25.5%. There was an increased incidence of late decelerations in the PGF(2α) group as compared to spontaneous and Pitocin-stimulated labors. While the success was high, the use of a drug which itself may cause fetal cardiovascular changes is not desirable, especially in those pregnancies already at risk.

Original languageEnglish
Pages (from-to)77-80
Number of pages4
JournalObstetrics and Gynecology
Issue number1
StatePublished - Jan 1 1978
Externally publishedYes


ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

O'Sullivan, M. J., Stone, M. L., Gugliucci, C. L., & Stephens, M. E. (1978). Induction of labor in the high risk pregnancy with PGF(2α). Obstetrics and Gynecology, 51(1), 77-80.