INDUCTION DE RECEPTEURS DES HORMONES GLUCOCORTICOIDES DANS DES CULTURES CONTINUES DE LYMPHOCUTES T HUMAINS

G. D. Bonnard; M. E. Lippman

INDUCTION DE RECEPTEURS DES HORMONES GLUCOCORTICOIDES DANS DES CULTURES CONTINUES DE LYMPHOCUTES T HUMAINS

Translated title of the contribution: Induction of glucocorticoid hormone receptors in human cultured T cells

G. D. Bonnard, M. E. Lippman

Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The presence is documented of high levels of specific glucocorticoid hormone receptors in human cultured T cells (CTC) maintained with a conditioned medium. When conditioned medium was removed from CTC for 24 h, receptor levels reverted to those of fresh, unstimulated lymphocytes. When conditioned medium, or phytohemagglutinin, was then added at various times before testing for glucocorticoid receptors, these stimuli were shown gradually to induce more receptor activity, beginning about 10 h of stimulation and increasing to 10-fold through 24 h.

Translated title of the contribution	Induction of glucocorticoid hormone receptors in human cultured T cells
Original language	French
Number of pages	1
Journal	Schweizerische Medizinische Wochenschrift
Volume	108
Issue number	41
State	Published - Jan 1 1978

ASJC Scopus subject areas

Medicine(all)

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title = "INDUCTION DE RECEPTEURS DES HORMONES GLUCOCORTICOIDES DANS DES CULTURES CONTINUES DE LYMPHOCUTES T HUMAINS",

abstract = "The presence is documented of high levels of specific glucocorticoid hormone receptors in human cultured T cells (CTC) maintained with a conditioned medium. When conditioned medium was removed from CTC for 24 h, receptor levels reverted to those of fresh, unstimulated lymphocytes. When conditioned medium, or phytohemagglutinin, was then added at various times before testing for glucocorticoid receptors, these stimuli were shown gradually to induce more receptor activity, beginning about 10 h of stimulation and increasing to 10-fold through 24 h.",

author = "Bonnard, {G. D.} and Lippman, {M. E.}",

year = "1978",

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language = "French",

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AU - Bonnard, G. D.

AU - Lippman, M. E.

PY - 1978/1/1

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N2 - The presence is documented of high levels of specific glucocorticoid hormone receptors in human cultured T cells (CTC) maintained with a conditioned medium. When conditioned medium was removed from CTC for 24 h, receptor levels reverted to those of fresh, unstimulated lymphocytes. When conditioned medium, or phytohemagglutinin, was then added at various times before testing for glucocorticoid receptors, these stimuli were shown gradually to induce more receptor activity, beginning about 10 h of stimulation and increasing to 10-fold through 24 h.

AB - The presence is documented of high levels of specific glucocorticoid hormone receptors in human cultured T cells (CTC) maintained with a conditioned medium. When conditioned medium was removed from CTC for 24 h, receptor levels reverted to those of fresh, unstimulated lymphocytes. When conditioned medium, or phytohemagglutinin, was then added at various times before testing for glucocorticoid receptors, these stimuli were shown gradually to induce more receptor activity, beginning about 10 h of stimulation and increasing to 10-fold through 24 h.

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