Increasing the complexity of periodic protein nanostructures by the rolling-circle-amplified synthesis of aptamers

Zoya Cheglakov, Yossi Weizmann, Adam B. Braunschweig, Ofer I. Wilner, Itamar Willner

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

(Figure Presented) The biomachinery of rolling-circle amplification relying on protein-aptamer interactions on DNA scaffolds was used to create one-dimensional DNA-protein/DNA-protein-nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.

Original languageEnglish (US)
Pages (from-to)126-130
Number of pages5
JournalAngewandte Chemie - International Edition
Volume47
Issue number1
DOIs
StatePublished - Jan 7 2008

Keywords

  • Aptamers
  • DNA
  • Nanoparticles
  • Nanostructures
  • Self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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