Abstract
The concentration of l-epinephrine hydrochloride necessary to inhibit lymphocyte transformation by 50% (I50 value) was determined in vitro for nine patients with primary open-angle glaucoma (POAG) and in seven controls. The lymphocytes of the patients with POAG were significantly (P<.05) more responsive. This result is consistent with the hypothesis that patients with POAG have an increased responsiveness to agents that elevate intracellular cyclic adenosine monophosphate levels.
Original language | English (US) |
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Pages (from-to) | 855-856 |
Number of pages | 2 |
Journal | Archives of ophthalmology |
Volume | 95 |
Issue number | 5 |
DOIs | |
State | Published - May 1977 |
Externally published | Yes |
Keywords
- Glaucoma
- cyclic adenosine monophosphate
- epinephrine hydrochloride
- lymphocytes
ASJC Scopus subject areas
- Ophthalmology