Abstract
The concentration of l-epinephrine hydrochloride necessary to inhibit lymphocyte transformation by 50% (I50 value) was determined in vitro for nine patients with primary open-angle glaucoma (POAG) and in seven controls. The lymphocytes of the patients with POAG were significantly (P<.05) more responsive. This result is consistent with the hypothesis that patients with POAG have an increased responsiveness to agents that elevate intracellular cyclic adenosine monophosphate levels.
| Original language | English |
|---|---|
| Pages (from-to) | 855-856 |
| Number of pages | 2 |
| Journal | Archives of Ophthalmology |
| Volume | 95 |
| Issue number | 5 |
| State | Published - Dec 1 1977 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Increased cellular responsiveness to epinephrine in primary open-angle glaucoma. / Palmberg, Paul; Hajek, S.; Cooper, D.; Becker, B.
In: Archives of Ophthalmology, Vol. 95, No. 5, 01.12.1977, p. 855-856.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased cellular responsiveness to epinephrine in primary open-angle glaucoma
AU - Palmberg, Paul
AU - Hajek, S.
AU - Cooper, D.
AU - Becker, B.
PY - 1977/12/1
Y1 - 1977/12/1
N2 - The concentration of l-epinephrine hydrochloride necessary to inhibit lymphocyte transformation by 50% (I50 value) was determined in vitro for nine patients with primary open-angle glaucoma (POAG) and in seven controls. The lymphocytes of the patients with POAG were significantly (P<.05) more responsive. This result is consistent with the hypothesis that patients with POAG have an increased responsiveness to agents that elevate intracellular cyclic adenosine monophosphate levels.
AB - The concentration of l-epinephrine hydrochloride necessary to inhibit lymphocyte transformation by 50% (I50 value) was determined in vitro for nine patients with primary open-angle glaucoma (POAG) and in seven controls. The lymphocytes of the patients with POAG were significantly (P<.05) more responsive. This result is consistent with the hypothesis that patients with POAG have an increased responsiveness to agents that elevate intracellular cyclic adenosine monophosphate levels.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017610189&partnerID=8YFLogxK
M3 - Article
C2 - 193479
AN - SCOPUS:0017610189
VL - 95
SP - 855
EP - 856
JO - JAMA Ophthalmology
JF - JAMA Ophthalmology
SN - 2168-6165
IS - 5
ER -