Increased and prolonged LH-RH/FSH-RH activity of synthetic (D-Ala6, Des-Gly-NH2 10)-LH-RH-ethylamide in normal women

J. Soria, A. Zarate, E. S. Canales, A. Ayala, A. V. Schally, D. H. Coy, E. J. Coy, A. J. Kastin

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A synthetic LH-RH analogue (D-Ala6, Des-Gly-NH2 10)-LH-RH ethylamide exhibited an increased and prolonged LH-RH/FSH-RH activity in normal women. The integrated amounts of LH and FSH levels for this LH-RH analogue were about nine and five times greater than for the same doses of synthetic LH-RH. It is expected that this synthetic LH-RH analogue might yield more positive results than with LH-RH when used in infertility problems.

Original languageEnglish (US)
Pages (from-to)145-146
Number of pages2
JournalAmerican journal of obstetrics and gynecology
Issue number2
StatePublished - Sep 15 1975
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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