Abstract
Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.
| Original language | English |
|---|---|
| Pages (from-to) | 598-600 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 51 |
| Issue number | 2 |
| State | Published - Aug 1 1998 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Inclusion body myositis in twins. / Amato, Anthony A.; Shebert, Robert T.
In: Neurology, Vol. 51, No. 2, 01.08.1998, p. 598-600.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Inclusion body myositis in twins
AU - Amato, Anthony A.
AU - Shebert, Robert T.
PY - 1998/8/1
Y1 - 1998/8/1
N2 - Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.
AB - Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.
UR - http://www.scopus.com/inward/record.url?scp=0031781405&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031781405&partnerID=8YFLogxK
M3 - Article
VL - 51
SP - 598
EP - 600
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 2
ER -