Inclusion body myositis in twins

Anthony A. Amato, Robert T. Shebert

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.

Original languageEnglish
Pages (from-to)598-600
Number of pages3
JournalNeurology
Volume51
Issue number2
StatePublished - Aug 1 1998
Externally publishedYes

Fingerprint

Inclusion Body Myositis
Muscle Weakness
Genetic Predisposition to Disease
Age of Onset
Forearm
Inflammation
Biopsy
Muscles

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Amato, A. A., & Shebert, R. T. (1998). Inclusion body myositis in twins. Neurology, 51(2), 598-600.

Inclusion body myositis in twins. / Amato, Anthony A.; Shebert, Robert T.

In: Neurology, Vol. 51, No. 2, 01.08.1998, p. 598-600.

Research output: Contribution to journalArticle

Amato, AA & Shebert, RT 1998, 'Inclusion body myositis in twins', Neurology, vol. 51, no. 2, pp. 598-600.
Amato AA, Shebert RT. Inclusion body myositis in twins. Neurology. 1998 Aug 1;51(2):598-600.
Amato, Anthony A. ; Shebert, Robert T. / Inclusion body myositis in twins. In: Neurology. 1998 ; Vol. 51, No. 2. pp. 598-600.
@article{d5f73c9f03fc4d028706288413bfd3e1,
title = "Inclusion body myositis in twins",
abstract = "Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.",
author = "Amato, {Anthony A.} and Shebert, {Robert T.}",
year = "1998",
month = "8",
day = "1",
language = "English",
volume = "51",
pages = "598--600",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Inclusion body myositis in twins

AU - Amato, Anthony A.

AU - Shebert, Robert T.

PY - 1998/8/1

Y1 - 1998/8/1

N2 - Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.

AB - Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s- IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.

UR - http://www.scopus.com/inward/record.url?scp=0031781405&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031781405&partnerID=8YFLogxK

M3 - Article

VL - 51

SP - 598

EP - 600

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 2

ER -