Incidental prostatic adenocarcinoma in patients undergoing radical cystoprostatectomy for bladder cancer

F. Abbas, D. Hochberg, Francisco Civantos, M. Soloway

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89 Citations (Scopus)

Abstract

To determine if patients with bladder cancer have a higher incidence of unsuspected prostate cancer, 40 cases were studied. All except one case had no evidence of prostate cancer on preoperative clinical assessment. Detailed pathological evaluation of cystoprostatectomy specimens with sections at 2- to 3-mm intervals was done. Adenocarcinoma of the prostate was identified in 18 of 40 patients (45%). Multifocal prostatic intraepithelial neoplasia (PIN) was present in 19 cases (47.5%); 4 (10%) without an associated prostate cancer and 15 (37.5%) in conjunction with adenocarcinoma of the prostate. Twelve cases of unsuspected prostate cancer were stage pT 1a, 4 were pT 1b, and 2 were pT3. No patients exhibited nodal or distant metastases by the prostate cancer. At a mean follow-up of 15.2 months (range 3-34 months), 37 of the 40 patients are alive. Among prostate cancer patients, no clinical or biochemical evidence of disease recurrence or prostate cancer related mortality has been observed. Our findings support the previously reported high incidence rate of prostate cancer in patients undergoing cystoprostatectomy for bladder cancer. This, though, may not be higher than the observed incidence in an age-matched general population. We recommend DRE and PSA as part of the bladder cancer workup in males, and complete removal of the prostate at cystoprostatectomy to prevent the dilemma of residual prostate cancer.

Original languageEnglish
Pages (from-to)322-326
Number of pages5
JournalEuropean Urology
Volume30
Issue number3
StatePublished - Nov 11 1996

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Urinary Bladder Neoplasms
Prostatic Neoplasms
Adenocarcinoma
Prostate
Incidence
Prostatic Intraepithelial Neoplasia
Residual Neoplasm
Neoplasm Metastasis
Recurrence
Mortality
Population

Keywords

  • Bladder cancer
  • Cystoprostatectomy
  • Incidental cancer
  • Prostate cancer

ASJC Scopus subject areas

  • Urology

Cite this

Incidental prostatic adenocarcinoma in patients undergoing radical cystoprostatectomy for bladder cancer. / Abbas, F.; Hochberg, D.; Civantos, Francisco; Soloway, M.

In: European Urology, Vol. 30, No. 3, 11.11.1996, p. 322-326.

Research output: Contribution to journalArticle

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