TY - JOUR
T1 - Incidence, risk factors, and prognosis of inhospital heart failure after percutaneous coronary intervention
T2 - Insight from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2)
AU - Aboufakher, Rabeea
AU - Riba, Arthur
AU - Jani, Sandeep M.
AU - Goswami, Raj
AU - Schwartz, Steven
AU - Lins, Sandra
AU - Gardin, Julius
AU - Smith, Dean E.
AU - Kline-Rogers, Eva
AU - Share, David
AU - Moscucci, Mauro
PY - 2005/9/1
Y1 - 2005/9/1
N2 - Background: Prior history of heart failure (HF) has been shown to be a predictor of poor outcomes after percutaneous coronary intervention (PCI). Clinical predictors of the development of inhospital HF and its prognostic significance after PCI have yet to be defined. In this study, we sought to identify the incidence, risk factors, and prognosis of inhospital HF after PCI. Methods: Using a contemporary registry of consecutive PCIs, the incidence of HF after PCI was identified. Multivariate logistic regression analysis was used to determine predictors of the development of HF after PCI as well as the impact of HF on inhospital mortality. Results: The incidence of HF after PCI in the overall patient population was 1.4%. Independent predictors of HF were female sex, age ≥60 years, exceeding a maximum weight- and creatinine-adjusted contrast dose, diabetes, prior HF, prior gastrointestinal bleeding, prior chronic obstructive pulmonary disease, history of atrial fibrillation, American College of Cardiology type B2 or C vessel, emergency PCI, ejection fraction <50%, myocardial infarction with or without cardiogenic shock, and repeat angiography. After adjustment for comorbidities, the development of HF was independently associated with an increased risk of inhospital death (adjusted OR 2.48, 95% CI 1.77-3.48). Conclusions: The development of HF is a relatively uncommon occurrence after PCI and is associated with a poor prognosis. The identification of risk factors for HF could foster the development of interventions aimed toward its prevention in high-risk patients.
AB - Background: Prior history of heart failure (HF) has been shown to be a predictor of poor outcomes after percutaneous coronary intervention (PCI). Clinical predictors of the development of inhospital HF and its prognostic significance after PCI have yet to be defined. In this study, we sought to identify the incidence, risk factors, and prognosis of inhospital HF after PCI. Methods: Using a contemporary registry of consecutive PCIs, the incidence of HF after PCI was identified. Multivariate logistic regression analysis was used to determine predictors of the development of HF after PCI as well as the impact of HF on inhospital mortality. Results: The incidence of HF after PCI in the overall patient population was 1.4%. Independent predictors of HF were female sex, age ≥60 years, exceeding a maximum weight- and creatinine-adjusted contrast dose, diabetes, prior HF, prior gastrointestinal bleeding, prior chronic obstructive pulmonary disease, history of atrial fibrillation, American College of Cardiology type B2 or C vessel, emergency PCI, ejection fraction <50%, myocardial infarction with or without cardiogenic shock, and repeat angiography. After adjustment for comorbidities, the development of HF was independently associated with an increased risk of inhospital death (adjusted OR 2.48, 95% CI 1.77-3.48). Conclusions: The development of HF is a relatively uncommon occurrence after PCI and is associated with a poor prognosis. The identification of risk factors for HF could foster the development of interventions aimed toward its prevention in high-risk patients.
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U2 - 10.1016/j.ahj.2004.12.011
DO - 10.1016/j.ahj.2004.12.011
M3 - Article
C2 - 16169323
AN - SCOPUS:24944492933
VL - 150
SP - 455
EP - 458
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 3
ER -