Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response

Weiwei Dang, George L. Sutphin, Jean A. Dorsey, Gabriel L. Otte, Kajia Cao, Rocco M. Perry, Jennifer J. Wanat, Dimitra Saviolaki, Christopher J. Murakami, Scott Tsuchiyama, Brett Robison, Brian D. Gregory, Michiel Vermeulen, Ramin Shiekhattar, F. Brad Johnson, Brian K. Kennedy, Matt Kaeberlein, Shelley L. Berger

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Medicine & Life Sciences