In vivo intravascular ultrasound in human ileo-femoral vessels

Marwan Tabbara, Douglas Cavaye, George Kopchok, Rodney White

Research output: Contribution to journalConference articlepeer-review


This study evaluates the ability of intravascular ultrasound (IUS) to image ormal and mildly diseased human ileo-femoral vessels during angioplasty or vascular bypass procedures. Five Fr. and 8Fr. rotating A scan IUS catheters were used to obtain 43 images in 4 superficial femoral arteries, and 5 iliac arteries in 8 vascular surgery patients. Luminal cross sectional (LCS) areas measured by IUS were compared to LCS areas calculated by uniplanar angiography (ANGIO) at the same location in the vessel. The correlation between the areas (IUS vs ANGIO) for all images was significant (n=43, r=0.90, P<0.05). Mean LCS area calculated from ANGIO (33.7 ± 21 mm2) was greater than LCS area measured by IUS (30.6 ± 19.5 mm2) with n=43; P=0.02. In addition to providing accurate luminal determinations, IUS images displayed transmural morphology, the location of the atherosclerotic lesions and the thickness of the vessel wall. We conclude that IUS imaging provides accurate, novel information regarding human vessel wall anatomy and luminal dimensions. This technology may play a significant role in future diagnostic and interventional therapies.

Original languageEnglish (US)
Pages (from-to)208-216
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jan 1 1991
Externally publishedYes
EventProceedings of Diagnostic and Therapeutic Cardiovascular Interventions - Los Angeles, CA, USA
Duration: Jan 20 1991Jan 22 1991

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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