In vivo endoscopic assessment of arterioarterial anastomoses

Insight into their hemodynamic function

T. Murakoshi, R. A. Quintero, P. W. Bornick, M. H. Allen

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objective: To assess endoscopically the hemodynamic function of arterioarterial (AA) anastomoses in twin-twin transfusion syndrome (TTTS) and monochorionic selective intrauterine growth restriction (IUGR). Materials and methods: The videotapes of TTTS and IUGR patients undergoing laser surgery between July 1997 and December 2001 were reviewed for the presence of AA anastomoses. The hemodynamic equator was defined as the site within the AA anastomosis with color flashing. AA anastomoses were classified as having unidirectional flow, having bi-directional flow, or being non-functional, depending on whether the hemodynamic equator reached a returning vein to one, both, or neither twin, respectively. TTTS was classified in stages as previously described. Results: AA anastomoses were present in 35/183 (19.1%) of TTTS and in 12/24 (50%) IUGR patients. Of these, the hemodynamic equator was visible in 8/35 (22.8%) TTTS patients (all in stage III, and mostly in atypical stage III) and in 6/12 (50%) IUGR patients (overall 14/47, 29.8%). Of the 14 patients with a visible hemodynamic equator, 13 (92.8%) AA anastomoses showed unidirectional (9/13, 69.2% from the smaller to the larger twin) flow, and only 1/14 (7.1%) showed bi-directional flow. Conclusion: The hemodynamic equator is visible in approximately 30% of patients with AA anastomoses. Within this group, most AA anastomoses behave as functional arteriovenous anastomoses, and the direction of flow can be from the smaller to the larger twin or vice versa. The data suggest a correlation between sonographic findings and placental vascular design, also implying possible interfetal oxygenation differences. Further assessment of the functional behavior of AA anastomoses is warranted to understand the pathophysiology of TTTS and selective IUGR.

Original languageEnglish
Pages (from-to)247-255
Number of pages9
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume14
Issue number4
StatePublished - Oct 1 2003

Fingerprint

Fetofetal Transfusion
Hemodynamics
Growth
Arteriovenous Anastomosis
Videotape Recording
Laser Therapy
Blood Vessels
Veins
Color

Keywords

  • Anastomosis
  • Fetoscope
  • Growth restriction
  • Twin-twin transfusion syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

In vivo endoscopic assessment of arterioarterial anastomoses : Insight into their hemodynamic function. / Murakoshi, T.; Quintero, R. A.; Bornick, P. W.; Allen, M. H.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 14, No. 4, 01.10.2003, p. 247-255.

Research output: Contribution to journalArticle

Murakoshi, T. ; Quintero, R. A. ; Bornick, P. W. ; Allen, M. H. / In vivo endoscopic assessment of arterioarterial anastomoses : Insight into their hemodynamic function. In: Journal of Maternal-Fetal and Neonatal Medicine. 2003 ; Vol. 14, No. 4. pp. 247-255.
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abstract = "Objective: To assess endoscopically the hemodynamic function of arterioarterial (AA) anastomoses in twin-twin transfusion syndrome (TTTS) and monochorionic selective intrauterine growth restriction (IUGR). Materials and methods: The videotapes of TTTS and IUGR patients undergoing laser surgery between July 1997 and December 2001 were reviewed for the presence of AA anastomoses. The hemodynamic equator was defined as the site within the AA anastomosis with color flashing. AA anastomoses were classified as having unidirectional flow, having bi-directional flow, or being non-functional, depending on whether the hemodynamic equator reached a returning vein to one, both, or neither twin, respectively. TTTS was classified in stages as previously described. Results: AA anastomoses were present in 35/183 (19.1{\%}) of TTTS and in 12/24 (50{\%}) IUGR patients. Of these, the hemodynamic equator was visible in 8/35 (22.8{\%}) TTTS patients (all in stage III, and mostly in atypical stage III) and in 6/12 (50{\%}) IUGR patients (overall 14/47, 29.8{\%}). Of the 14 patients with a visible hemodynamic equator, 13 (92.8{\%}) AA anastomoses showed unidirectional (9/13, 69.2{\%} from the smaller to the larger twin) flow, and only 1/14 (7.1{\%}) showed bi-directional flow. Conclusion: The hemodynamic equator is visible in approximately 30{\%} of patients with AA anastomoses. Within this group, most AA anastomoses behave as functional arteriovenous anastomoses, and the direction of flow can be from the smaller to the larger twin or vice versa. The data suggest a correlation between sonographic findings and placental vascular design, also implying possible interfetal oxygenation differences. Further assessment of the functional behavior of AA anastomoses is warranted to understand the pathophysiology of TTTS and selective IUGR.",
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KW - Growth restriction

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