In vitro synthesis of tissue‐specific type ii collagen by healing cartilage

Herman S. Cheung, Kenneth L. Lynch, Roger P. Johnson, Bruce J. Brewer

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

The healing of surgically induced defects in mature rabbits' hyaline cartilage was examined histologically and biochemically. The subchondral bone underneath the lesion was the source of repair. At the end of the first month, mushroom-shaped chondroid buds were seen sprouting from the subchondral bone. By the 10th wk, these buds fused to a cartilagenous plug filling the lesion. The repaired cartilage synthesized type II collagen.

Original languageEnglish (US)
Pages (from-to)211-219
Number of pages9
JournalArthritis & Rheumatism
Volume23
Issue number2
DOIs
StatePublished - Jan 1980

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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