Abstract
The in-vitro and in-vivo Nuclear Magnetic Resonance (NMR) Imaging and spectroscopy to non-invasively monitor the viability and function of a bioartificial pancreas was described. All in vitro data were obtained from single beads with very high resolution, which allowed the experts to visualize the reorganization of cells with time in culture. For the in vivo studies, a retrievable design consisting of alginate/poly-L-lysine/alginate (APA) beads contained in an agarose gel was used. It was shown that the application of these NMR techniques is very useful in visualizing cell growth within the beads as well as monitoring aspects of intracellular metabolic activity that correlates with cell viability.
| Original language | English |
|---|---|
| Title of host publication | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products |
| State | Published - Dec 1 2002 |
| Event | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products - Atlanta, GA, United States Duration: Oct 13 2002 → Oct 16 2002 |
Other
| Other | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products |
|---|---|
| Country | United States |
| City | Atlanta, GA |
| Period | 10/13/02 → 10/16/02 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
In-vitro and In-vivo nuclear magnetic resonance imaging and spectroscopy of a bioartificial pancreas. / Constantinidis, Ioannis; Stabler, Cherie; Grant, Samuel; Simpson, Nicholas; Blackband, Steve; Long, Robert; Sambanis, Athanassios.
Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products. 2002. MS-3.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - In-vitro and In-vivo nuclear magnetic resonance imaging and spectroscopy of a bioartificial pancreas
AU - Constantinidis, Ioannis
AU - Stabler, Cherie
AU - Grant, Samuel
AU - Simpson, Nicholas
AU - Blackband, Steve
AU - Long, Robert
AU - Sambanis, Athanassios
PY - 2002/12/1
Y1 - 2002/12/1
N2 - The in-vitro and in-vivo Nuclear Magnetic Resonance (NMR) Imaging and spectroscopy to non-invasively monitor the viability and function of a bioartificial pancreas was described. All in vitro data were obtained from single beads with very high resolution, which allowed the experts to visualize the reorganization of cells with time in culture. For the in vivo studies, a retrievable design consisting of alginate/poly-L-lysine/alginate (APA) beads contained in an agarose gel was used. It was shown that the application of these NMR techniques is very useful in visualizing cell growth within the beads as well as monitoring aspects of intracellular metabolic activity that correlates with cell viability.
AB - The in-vitro and in-vivo Nuclear Magnetic Resonance (NMR) Imaging and spectroscopy to non-invasively monitor the viability and function of a bioartificial pancreas was described. All in vitro data were obtained from single beads with very high resolution, which allowed the experts to visualize the reorganization of cells with time in culture. For the in vivo studies, a retrievable design consisting of alginate/poly-L-lysine/alginate (APA) beads contained in an agarose gel was used. It was shown that the application of these NMR techniques is very useful in visualizing cell growth within the beads as well as monitoring aspects of intracellular metabolic activity that correlates with cell viability.
UR - http://www.scopus.com/inward/record.url?scp=18644366409&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=18644366409&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:18644366409
BT - Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products
ER -